4-Chloro-5-methoxybenzofuran

Base Information

• Chemical Name: 4-Chloro-5-methoxybenzofuran
• CAS No.: 77440-97-2
• Molecular Formula: C₉H₇ClO₂
• Molecular Weight: 182.606
• DSSTox Substance ID: DTXSID70504505
• Wikidata: Q82359053
• Mol file: 77440-97-2.mol

Synonyms:4-CHLORO-5-METHOXYBENZOFURAN;77440-97-2;4-chloro-5-methoxy-1-benzofuran;DTXSID70504505;CDA44097

Chemical Property of 4-Chloro-5-methoxybenzofuran

Chemical Property:

• PSA: 22.37000
• LogP: 3.09480
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 182.0134572
• Heavy Atom Count: 12
• Complexity: 163

Purity/Quality:

≥99% ^*data from raw suppliers

4-Chloro-5-methoxybenzofuran 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C2=C(C=C1)OC=C2)Cl

Technology Process of 4-Chloro-5-methoxybenzofuran

There total 1 articles about 4-Chloro-5-methoxybenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

5-methoxybenzofuran (13391-28-1) → chloro-6 methoxy-5 benzofuranne (77440-98-3) + chloro-2 methoxy-5 benzofuranne (77440-95-0) + chloro-4 methoxy-5 benzofuranne (77440-97-2) + chloro-3 methoxy-5 benzofuranne (77440-96-1)

Guidance literature:

With Nitroethane; pyridine hydrochloride; for 2h; Heating;

upstream raw materials:

5-methoxybenzofuran

Refernces