N-(4-Hydroxyphenyl)dodecanamide

Base Information

• Chemical Name: N-(4-Hydroxyphenyl)dodecanamide
• CAS No.: 103-98-0
• Molecular Formula: C18H29 N O2
• Molecular Weight: 291.434
• Hs Code.: 2924299090
• European Community (EC) Number: 203-164-3
• NSC Number: 166353
• UNII: C2C3U7Q3RE
• DSSTox Substance ID: DTXSID1059286
• Nikkaji Number: J182.173C
• Wikidata: Q81988729
• ChEMBL ID: CHEMBL227759
• Mol file: 103-98-0.mol

Synonyms:N-(4-Hydroxyphenyl)dodecanamide;4'-Hydroxydodecananilide;103-98-0;Dodecanamide, N-(4-hydroxyphenyl)-;N-Lauroyl-p-aminophenol;N-Lauroyl-4-aminophenol;Suconox-12;Suconox-112;N-Lavroyl-p-aminophenol;N-Lavroyl-para-aminophenol;Dodecananilide, 4'-hydroxy-;NSC 166353;C2C3U7Q3RE;EINECS 203-164-3;NSC-166353;NSC166353;4-(Dodecanoylamino)phenol;SUCONOX 12;UNII-C2C3U7Q3RE;SCHEMBL39445;N-(4-hydroxyphenyl)dodecanamid;CHEMBL227759;DTXSID1059286;N-(4-hydroxyphenyl)dodecananamide;STK247614;AKOS003646048;CS-0339756

Chemical Property of N-(4-Hydroxyphenyl)dodecanamide

Chemical Property:

• Vapor Pressure: 1.16E-09mmHg at 25°C
• Boiling Point: 475.4°C at 760 mmHg
• Flash Point: 241.3°C
• PSA: 49.33000
• Density: 1.018g/cm³
• LogP: 5.32460
• XLogP3: 6.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 11
• Exact Mass: 291.219829168
• Heavy Atom Count: 21
• Complexity: 260

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCC(=O)NC1=CC=C(C=C1)O

Technology Process of N-(4-Hydroxyphenyl)dodecanamide

There total 7 articles about N-(4-Hydroxyphenyl)dodecanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

lauric anhydride (645-66-9) + 4-amino-phenol (123-30-8) → 4-n-dodecanoylaminophenol (103-98-0)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 16h;

DOI:10.1016/j.bmc.2006.05.013

Reference yield: 84.0%

lauric acid (143-07-7) + 4-amino-phenol (123-30-8) → 4-n-dodecanoylaminophenol (103-98-0)

Guidance literature:

With 2-bromo-1-methyl-pyridinium iodide; triethylamine; In dichloromethane; at 60 ℃; for 0.75h;

DOI:10.1248/cpb.28.2941

Reference yield:

4-amino-phenol (123-30-8) + ethyl dodecanoyl carbonate (21260-90-2) → 4-n-dodecanoylaminophenol (103-98-0)

Guidance literature:

In water; acetonitrile; at 0 ℃; for 24h;

DOI:10.1055/s-0037-1611893

upstream raw materials:

lauric acid

4-acetaminophenol

4-amino-phenol

n-dodecanoyl chloride

Refernces

• 1、 Lyu, Bin,Yu, Yajin,Gao, Dangge,Wang, Yuefeng,Ma, Jianzhong. "Asymmetric sodium benzenesulfonate Gemini surfactant: Synthesis, properties and application". . p. 500 - 507. Retrieved 2019.
• 2、 -. "Piperidyl organosiloxanes and polymer substrates light-stabilized therewith". . . Retrieved 2008/06/13.