17BETA-ESTRADIOL-2,4,16,16-D4

Base Information

Chemical Name:17BETA-ESTRADIOL-2,4,16,16-D4
CAS No.:66789-03-5
Molecular Formula:C18H20D4O2
Molecular Weight:276.41
Hs Code.:

Synonyms:ESTRADIOL (2,4,16,16-D4);17BETA-ESTRADIOL-2,4,16,16-D4;17-Estradiol-d4;17β-Estradiol-2,4,16,16-d4;Estradiol-d4

Suppliers and Price of 17BETA-ESTRADIOL-2,4,16,16-D4

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
17β-Estradiol-d4
1mg
$ 403.00

TRC
17β-Estradiol-d4
10mg
$ 1070.00

Medical Isotopes, Inc.
17β-Estradiol-2,4,16,16-d4
10 mg
$ 290.00

American Custom Chemicals Corporation
ESTRADIOL-D4 95.00%
10MG
$ 1963.50

American Custom Chemicals Corporation
ESTRADIOL-D4 95.00%
1MG
$ 750.75

Total 11 raw suppliers

Chemical Property of 17BETA-ESTRADIOL-2,4,16,16-D4

Chemical Property:

PSA：40.46000
LogP:3.60920

Purity/Quality:

97% ^*data from raw suppliers

17β-Estradiol-d4 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Estradiol-d4 can be intended for use as an internal standard for the quantification of Estradiol by GC- or LC-mass spectrometry. Isotope labelled 17β-Estradiol (E888000), which is the major estrogen (1) secreted by the premenopausal ovary (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.

Technology Process of 17BETA-ESTRADIOL-2,4,16,16-D4

There total 4 articles about 17BETA-ESTRADIOL-2,4,16,16-D4 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 53866-34-5,350820-16-5
estrone-2,4,16,16-d₄

: 221093-45-4,66789-03-5
2,4,16,16,17-²H-estradiol-17β

Guidance literature:: With lithium aluminium deuteride; In tetrahydrofuran; at 20 ℃; for 2.5h;
DOI:10.1016/j.steroids.2005.08.001

Reference yield:

: 53866-34-5,350820-16-5
estrone-2,4,16,16-d₄

: 66789-03-5
17-β-estradiol-2,4,16,16-d₄

Guidance literature:: With sodium tetrahydroborate; In methanol;
DOI:10.1016/S0039-128X(00)00184-7

Reference yield:

: 53-16-7
Estrone

: 66789-03-5
17-β-estradiol-2,4,16,16-d₄

Guidance literature:: Multi-step reaction with 3 steps

1: methanol-d1; NaOMe

2: methanol-d1; DCl; D₂O

3: NaBH₄ / methanol

With sodium tetrahydroborate; diclazuril; deuteromethanol; water-d2; sodium methylate; In methanol;
DOI:10.1016/S0039-128X(00)00184-7