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Technology Process of Spinetoram

Spinetoram

Base Information
  • Chemical Name:Spinetoram
  • CAS No.:187166-40-1
  • Molecular Formula:C42H69NO10
  • Molecular Weight:748.004
  • Hs Code.:
  • Mol file:187166-40-1.mol
Spinetoram

Synonyms:Spinetoram (major component);Spinetoram (major component) [ISO];1H-as-Indaceno[3,2-d]oxacyclododecin-7,15-dione, 2-[(6-deoxy-3-O-ethyl-2,4-di-O-methyl-a-L-mannopyranosyl)oxy]-13-[[(2 R,5S,6R)-5-(dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-9-et hyl-2,3,3a,4,5,5a,5b,6,9,10,11,12,13,14,16a,16b-hexadecahydro-14-m ethyl-, (2R,3aR,5aR,5bS,9S,13S,14R,16aS,16bR)-;

Suppliers and Price of Spinetoram
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Spinetoram
  • 10mg
  • $ 145.00
  • American Custom Chemicals Corporation
  • SPINETORAM 95.00%
  • 5MG
  • $ 496.46
Total 86 raw suppliers
Chemical Property of Spinetoram
Chemical Property:
  • Boiling Point:803.5±65.0 °C(Predicted) 
  • PKA:8.62±0.60(Predicted) 
  • PSA：111.22000 
  • Density:1.15±0.1 g/cm3(Predicted) 
  • LogP:6.10150 
Purity/Quality:

99%, *data from raw suppliers

Spinetoram *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • General Description Spinetoram is a broad-spectrum, environmentally friendly insecticide derived from fermentation, known for its low toxicity to animals and humans. Semi-synthetic modifications, such as replacing D-forosamine with alternative sugar moieties, have been explored to enhance its synthesis efficiency and cost-effectiveness. While some analogues exhibit reduced insecticidal activity compared to spinetoram, certain derivatives demonstrate promising efficacy, highlighting the potential for developing novel insecticides through structural optimization of sugar components and substituent properties.
Refernces

Semi-synthesis and insecticidal activity of spinetoram J and its D-forosamine replacement analogues

10.3762/bjoc.14.207

The study focuses on the semi-synthesis and insecticidal activity of spinetoram J and its D-forosamine replacement analogues. Spinetoram, derived from fermentation, is a broad-spectrum insecticide that is environmentally friendly and non-toxic to animals and humans. The researchers improved the semi-synthesis process of spinetoram J by using 3-O-ethyl-2,4-di-O-methylrhamnose as both a reaction substrate and a protecting group, which simplified the synthesis steps and reduced costs. They also synthesized a range of D-forosamine replacement analogues and evaluated their insecticidal activities against Plutella xylostella larvae. Although the analogues did not match the potency of spinetoram, some showed only 20–40 times lower activity, with one analogue being nearly as active as spinosad. The findings suggest the potential for developing new insecticides by modifying sugar components in natural products and highlight the importance of the electrical properties of substituents in insecticidal activity.

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