2-(2-(4-broMophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione

Base Information

Chemical Name:2-(2-(4-broMophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione
CAS No.:1199556-86-9
Molecular Formula:C20H16BrNO4
Molecular Weight:414.255
Hs Code.:2934999090
Mol file:1199556-86-9.mol

Synonyms:2-[2-(4-bromophenyl)-5,8-dioxaspiro[3.4]oct-2-yl]-1H-isoindole-1,3(2H)-dione;2-(2-(4-bromophenyl)-5,8-dioxaspiro[3.4]oct-2-yl)isoindole-1,3-dione;QC-795;2-(2-(4-Bromophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione;

Suppliers and Price of 2-(2-(4-broMophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(2-(4-Bromophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione 95+%
1g
$ 550.00

Chemenu
2-(2-(4-Bromophenyl)-5,8-dioxaspiro-[3.4]octan-2-yl)isoindoline-1,3-dione 95%
1g
$ 519.00

American Custom Chemicals Corporation
2-(2-(4-BROMOPHENYL)-5,8-DIOXASPIRO[3.4]OCTAN-2-YL)ISOINDOLINE-1,3-DIONE 95.00%
5MG
$ 497.35

Alichem
2-(2-(4-Bromophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione
1g
$ 452.48

Total 5 raw suppliers

Chemical Property of 2-(2-(4-broMophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione

Chemical Property:

Boiling Point:529.1±50.0 °C(Predicted)
PKA:-2.37±0.20(Predicted)
PSA：55.84000
Density:1.65±0.1 g/cm3(Predicted)
LogP:3.41540
Storage Temp.:2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-(4-Bromophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(2-(4-broMophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione

There total 2 articles about 2-(2-(4-broMophenyl)-5,8-dioxaspiro[3.4]octan-2-yl)isoindoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22509-74-6
N-ethoxycarbonylphthalimide

: 1199556-85-8
2-(4-bromophenyl)-5,8-dioxaspiro[3.4]octan-2-amine

: 1199556-86-9
2-[2-(4-bromophenyl)-5,8-dioxaspiro[3.4]oct-2-yl]-1H-isoindole-1,3(2H)-dione

Guidance literature:: With triethylamine; In dichloromethane; at 80 ℃; for 5h;

Reference yield:

: 1199557-05-5
tert-butyl [2-(4-bromophenyl)-5,8-dioxaspiro[3.4]oct-2-yl]carbamate

: 1199556-86-9
2-[2-(4-bromophenyl)-5,8-dioxaspiro[3.4]oct-2-yl]-1H-isoindole-1,3(2H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / 1 h / 20 °C

2: triethylamine / chloroform / 70 °C

With triethylamine; trifluoroacetic acid; In chloroform;

Reference yield:

: 1199556-86-9
2-[2-(4-bromophenyl)-5,8-dioxaspiro[3.4]oct-2-yl]-1H-isoindole-1,3(2H)-dione

: 1199556-90-5
2-{trans-3-hydroxy-3-methyl-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclobutyl}-1H-isoindole-1,3(2H)-dione

Guidance literature:: Multi-step reaction with 3 steps

1: toluenesulfonic acid monohydrate / acetone / 48 h / Reflux

2: tetrahydrofuran; dichloromethane / 1 h / -20 °C

3: potassium acetate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / dimethyl sulfoxide / 3 h / 80 °C

With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In tetrahydrofuran; dichloromethane; dimethyl sulfoxide; acetone;