4,4'-(Propane-1,3-diyl)bismorpholine

Base Information

• Chemical Name: 4,4'-(Propane-1,3-diyl)bismorpholine
• CAS No.: 48152-09-6
• Molecular Formula: C11H22 N2 O2
• Molecular Weight: 214.308
• European Community (EC) Number: 256-361-1
• NSC Number: 13539
• UNII: L6Y54WE9R8
• DSSTox Substance ID: DTXSID40197443
• Nikkaji Number: J319.974F
• Wikidata: Q83070309
• Mol file: 48152-09-6.mol

Synonyms:1,3-Dimorpholinopropane;48152-09-6;4,4'-(Propane-1,3-diyl)bismorpholine;4-(3-morpholin-4-ylpropyl)morpholine;L6Y54WE9R8;4-[3-(MORPHOLIN-4-YL)PROPYL]MORPHOLINE;EINECS 256-361-1;NSC-13539;4,4'-(1,3-Propanediyl)bis(morpholine);Morpholine, 4,4'-(1,3-propanediyl)bis-;NSC13539;UNII-L6Y54WE9R8;SCHEMBL1998867;DTXSID40197443;NSC 13539;AKOS002662754;AS-62552

Chemical Property of 4,4'-(Propane-1,3-diyl)bismorpholine

Chemical Property:

• Boiling Point: 323.4°Cat760mmHg
• PKA: 7.76±0.10(Predicted)
• Flash Point: 96.4°C
• Density: 1.034g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 214.168127949
• Heavy Atom Count: 15
• Complexity: 148

Purity/Quality:

99% ^*data from raw suppliers

1,3-Dimorpholinopropane 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1CCCN2CCOCC2

Technology Process of 4,4'-(Propane-1,3-diyl)bismorpholine

There total 3 articles about 4,4'-(Propane-1,3-diyl)bismorpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

3-Morpholin-4-yl-propionitrile (4542-47-6) → 1,3-bis-morpholinopropane (48152-09-6) + C13H28N2O

Guidance literature:

With sodium tetrahydroborate; hydrogen; nickel dichloride; In isopropyl alcohol; at 70 ℃; for 14h; under 760.051 Torr;

DOI:10.1134/S1070363216020110

Reference yield:

morpholine (110-91-8,99108-56-2) + 1,3-dibromo-propane (109-64-8) → 1,3-bis-morpholinopropane (48152-09-6)

Guidance literature:

With benzene;

DOI:10.1021/ja01649a052

Reference yield:

→ 1,3-bis-morpholinopropane (48152-09-6)

Guidance literature:

Morpholin,1,3-Dibrompropan/C6H6/NaOH;

upstream raw materials:

morpholine

1,3-dibromo-propane

3-Morpholin-4-yl-propionitrile

Refernces