3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoic acid

Base Information

Chemical Name:3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoic acid
CAS No.:171002-19-0
Molecular Formula:C17H16ClNO3
Molecular Weight:317.76684
Hs Code.:2924299090
DSSTox Substance ID:DTXSID60394997
Nikkaji Number:J3.466.042E
Mol file:171002-19-0.mol

Synonyms:3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoic acid;171002-19-0;3-(4-chlorophenyl)-3-[(2-phenylacetyl)amino]propanoic Acid;3-(2-phenylacetaMido)-3-(4-chlorophenyl)propanoic acid;Oprea1_603818;SCHEMBL6953151;3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoicacid;DTXSID60394997;SC1170;AKOS015919744;A881966;3-(4-Chlorophenyl)-3-(phenylacetamido)propionic acid;3-(4-Chlorophenyl)-3-(phenylacetylamino)propanoic acid

Suppliers and Price of 3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
3-(4-chlorophenyl)-3-(2-phenylacetamido)propanoicacid 95%
1g
$ 282.00

American Custom Chemicals Corporation
3-(4-CHLOROPHENYL)-3-(2-PHENYLACETAMIDO)PROPANOIC ACID 95.00%
5MG
$ 498.17

Total 12 raw suppliers

Chemical Property of 3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoic acid

Chemical Property:

PSA：69.89000
Density:1.293
LogP:4.05500
Storage Temp.:2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:317.0818711
Heavy Atom Count:22
Complexity:374

Purity/Quality:

97% ^*data from raw suppliers

3-(4-chlorophenyl)-3-(2-phenylacetamido)propanoicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(=O)NC(CC(=O)O)C2=CC=C(C=C2)Cl

Technology Process of 3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoic acid

There total 2 articles about 3-(4-Chlorophenyl)-3-(2-phenylacetamido)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 19947-39-8,131690-61-4
3-amino-3-(4-chlorophenyl)propionic acid

: 103-80-0
phenylacetyl chloride

: 171002-19-0
β-(N-phenylacetylamino)-β-(4-chlorophenyl)propionic acid

Guidance literature:: With triethylamine; In water; acetone; at -5 - 20 ℃; for 5.5h;
DOI:10.1080/10826068.2012.719847

Reference yield:

: 104-88-1
4-chlorobenzaldehyde

: 171002-19-0
β-(N-phenylacetylamino)-β-(4-chlorophenyl)propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / ethanol / 6 h / Reflux

2: triethylamine / acetone; water / 5.5 h / -5 - 20 °C

With ammonium acetate; triethylamine; In ethanol; water; acetone;
DOI:10.1080/10826068.2012.719847

Reference yield: 70.0%

: 171002-19-0
β-(N-phenylacetylamino)-β-(4-chlorophenyl)propionic acid

: 131690-61-4
(R)-β-amino-β-(4-chlorophenyl)propionic acid

Guidance literature:: With potassium hydroxide; Ambient temperature; penicillin acylase (EC 3.5.1.11), pH 7.5;
DOI:10.1016/0957-4166(95)00204-3