N-t-Boc-valacyclovir

Base Information

Chemical Name:N-t-Boc-valacyclovir
CAS No.:502421-44-5
Molecular Formula:C18H28N6O6
Molecular Weight:424.457
Hs Code.:
Mol file:502421-44-5.mol

Synonyms:2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl N-(tert-butoxycarbonyl)-L-valinate; L-valine, N-[(1,1-dimethylethoxy)carbonyl]-, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester

Suppliers and Price of N-t-Boc-valacyclovir

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-t-Boc-valacyclovir
50mg
$ 446.00

Usbiological
N-t-Boc Valacyclovir
100mg
$ 446.00

TRC
N-t-BocValacyclovir
1g
$ 260.00

Biosynth Carbosynth
N-t-Boc-valacyclovir
1 g
$ 250.00

Biosynth Carbosynth
N-t-Boc-valacyclovir
500 mg
$ 150.00

Biosynth Carbosynth
N-t-Boc-valacyclovir
250 mg
$ 100.00

Biosynth Carbosynth
N-t-Boc-valacyclovir
100 mg
$ 60.00

Biosynth Carbosynth
N-t-Boc-valacyclovir
50 mg
$ 40.00

Total 33 raw suppliers

Chemical Property of N-t-Boc-valacyclovir

Chemical Property:

Vapor Pressure:0Pa at 25℃
Boiling Point:603.96℃
PKA:11.05±0.46(Predicted)
PSA：163.45000
Density:1.397g/cm³
LogP:1.74050
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Acetic Acid (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99.9% ^*data from raw suppliers

N-t-Boc-valacyclovir ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-t-Boc-valacyclovir

There total 3 articles about N-t-Boc-valacyclovir which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59277-89-3
acycloguanosine

: 13734-41-3
t-Boc-L-valine

: 502421-44-5
Boc-L-valacyclovir

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In pyridine; dichloromethane; at 0 - 20 ℃; for 50h;
DOI:10.1016/j.ejmech.2008.08.009

Reference yield:

: 59277-89-3
acycloguanosine

: 33294-55-2
(S)-2-(tert-butoxycarbonylamino)-3-methylbutanoic anhydride

: 502421-44-5
Boc-L-valacyclovir

Guidance literature:: With dmap; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1016/S1386-1425(03)00007-6

Reference yield:

: 13734-41-3
t-Boc-L-valine

: 502421-44-5
Boc-L-valacyclovir

Guidance literature:: Multi-step reaction with 2 steps

1: DCC / dimethylformamide / 1 h / 0 °C

2: DMAP / dimethylformamide / 24 h / 20 °C

With dmap; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide;
DOI:10.1016/S1386-1425(03)00007-6