2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione

Base Information

Chemical Name:2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione
CAS No.:110859-48-8
Molecular Formula:C20H20N2O3
Molecular Weight:336.39
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10471166
Mol file:110859-48-8.mol

Synonyms:110859-48-8;2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione;2-[(4-benzylmorpholin-2-yl)methyl]isoindole-1,3-dione;2-[(4-benzylmorpholin-2-yl)methyl]-2,3-dihydro-1H-isoindole-1,3-dione;N-[(4-benzyl-2-morpholinyl)methyl]phthalimide;2-(4-BENZYL-MORPHOLIN-2-YLMETHYL)-ISOINDOLE-1,3-DIONE;2-((4-BENZYLMORPHOLIN-2-YL)METHYL)ISOINDOLINE-1,3-DIONE;2-[[4-(Phenylmethyl)-2-morpholinyl]methyl]-1H-isoindole-1,3(2H)-dione;4-Benzyl-2-phthalimidomethylmorpholine;SCHEMBL1502135;DTXSID10471166;YAQSVEHQDFSDCR-UHFFFAOYSA-N;MFCD11101104;2-phthalimidomethyl-4-benzylmorpholine;AKOS008901119;SB64800;AS-30322;FT-0684507;EN300-100171;A894838;2-[(4-Benzylmorpholin-2-yl)methyl]-1H-isoindole-1,3(2H)-dione

Suppliers and Price of 2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(4-Benzyl-morpholin-2-ylmethyl)-isoindole-1,3-dione
100mg
$ 45.00

Matrix Scientific
2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione >90%
500mg
$ 237.00

Crysdot
2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione 95+%
1g
$ 391.00

Chemenu
2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione 95%
1g
$ 369.00

Alichem
2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione
1g
$ 438.45

Alichem
2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione
5g
$ 1048.38

AK Scientific
2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione
500mg
$ 369.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
2-(4-Benzyl-morpholin-2-ylmethyl)-isoindole-1,3-dione 95%+
5g
$ 340.75

Acints
2-(4-Benzyl-morpholin-2-ylmethyl)-isoindole-1,3-dione 95%+
10g
$ 500.25

Acints
2-(4-Benzyl-morpholin-2-ylmethyl)-isoindole-1,3-dione 95%+
5g
$ 340.75

Total 6 raw suppliers

Chemical Property of 2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione

Chemical Property:

PSA：49.85000
LogP:2.05940
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:336.14739250
Heavy Atom Count:25
Complexity:479

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Benzyl-morpholin-2-ylmethyl)-isoindole-1,3-dione ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(CN1CC2=CC=CC=C2)CN3C(=O)C4=CC=CC=C4C3=O

Technology Process of 2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione

There total 2 articles about 2-[(4-Benzylmorpholin-2-yl)methyl]isoindoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.6%

: 40987-25-5,186293-54-9
N-benzyl-2-chloromethylmorpholine

: 1074-82-4
potassium phtalimide

: 110859-48-8
N-[(4-benzyl-2-morpholinyl)methyl]phthalimide

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃;

Reference yield:

: 104-63-2
N-Benzylethanolamine

: 110859-48-8
N-[(4-benzyl-2-morpholinyl)methyl]phthalimide

Guidance literature:: Multi-step reaction with 2 steps

1: 2.) concd. H₂SO₄ / 1.) RT, 3 h, 2.) 150 deg C, 1 h

2: 83 percent / dimethylformamide / 5 h / Heating

With sulfuric acid; In N,N-dimethyl-formamide;
DOI:10.1021/jm00167a020