(S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate

Base Information

Chemical Name:(S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate
CAS No.:91229-86-6
Molecular Formula:C14H26BrNO4
Molecular Weight:352.269
Hs Code.:2924199090
DSSTox Substance ID:DTXSID10456771
Nikkaji Number:J763.935J
Wikidata:Q72512604
Mol file:91229-86-6.mol

Synonyms:91229-86-6;(S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate;Tert-butyl (2S)-5-bromo-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate;C14H26BrNO4;SCHEMBL13422138;DTXSID10456771;tert-butyl (S)-5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate;MFCD22576481;DS-5608;CS-0154599;F11556;tert-Butyl 5-bromo-N-(tert-butoxycarbonyl)-L-norvalinate;(S)-tert-Butyl5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate;N-(tert-Butoxycarbonyl)-5-bromo-L-norvaline tert-butyl ester;tert-butyl (2S)-5-bromo-2-{[(tert-butoxy)carbonyl]amino}pentanoate;L-Norvaline, 5-bromo-N-[(1,1-dimethylethoxy)carbonyl]-,1,1-dimethylethyl ester

Suppliers and Price of (S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Ambeed
(S)-tert-Butyl5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate 95+%
5g
$ 638.00

Ambeed
(S)-tert-Butyl5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate 95+%
1g
$ 239.00

Ambeed
(S)-tert-Butyl5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate 95+%
250mg
$ 119.00

Ambeed
(S)-tert-Butyl5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate 95+%
100mg
$ 79.00

AK Scientific
(S)-Tert-Butyl5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate
1g
$ 367.00

Activate Scientific
(S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate 97+% ee
5 g
$ 1383.00

Activate Scientific
(S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate 97+% ee
1 g
$ 545.00

Activate Scientific
(S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate 97+% ee
250 mg
$ 240.00

Total 11 raw suppliers

Chemical Property of (S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate

Chemical Property:

Boiling Point:402.7±40.0 °C(Predicted)
PKA:11.05±0.46(Predicted)
PSA：68.12000
Density:1.218
LogP:3.60090
Storage Temp.:2-8°C
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:351.10452
Heavy Atom Count:20
Complexity:331

Purity/Quality:

99%, ^*data from raw suppliers

(S)-tert-Butyl5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C(CCCBr)NC(=O)OC(C)(C)C
Isomeric SMILES:CC(C)(C)OC(=O)[C@H](CCCBr)NC(=O)OC(C)(C)C

Technology Process of (S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate

There total 20 articles about (S)-tert-Butyl 5-bromo-2-((tert-butoxycarbonyl)amino)pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 90194-99-3
tert-butyl (S)-2-<(tert-butyloxycarbonyl)amino>-5-hydroxypentanoate

: 91229-86-6
tert-butyl (S)-2-<(tert-butyloxycarbonyl)amino>-5-bromopentanoate

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 ℃; for 0.333333h;

Reference yield: 81.0%

: 24277-39-2
N-tert-butoxycarbonyl glutamic acid tert-butyl ester

: 91229-86-6
tert-butyl (S)-2-<(tert-butyloxycarbonyl)amino>-5-bromopentanoate

Guidance literature:: N-tert-butoxycarbonyl glutamic acid tert-butyl ester; With N-methyl-2-indolinone; chloroformic acid ethyl ester;

With sodium tetrahydroborate; In methanol;

With carbon tetrabromide; triphenylphosphine;
DOI:10.1016/S0040-4039(03)01222-X

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 91229-86-6
tert-butyl (S)-2-<(tert-butyloxycarbonyl)amino>-5-bromopentanoate

Guidance literature:: Multi-step reaction with 5 steps

1: NEt₃ / dioxane; H₂O / 4 h / Ambient temperature

2: 78 percent / H₂ / 5percent Pd/C / ethanol; H₂O / 12 h

3: NEt₃ / tetrahydrofuran / 0.5 h / -10 °C

4: NaBH₄ / H₂O; tetrahydrofuran / 4 h / Ambient temperature

5: 77 percent / CBr₄ / PPh₃ / tetrahydrofuran / 1) ca.15 deg C, 10 min 2) r.t.

With sodium tetrahydroborate; carbon tetrabromide; hydrogen; triethylamine; triphenylphosphine; palladium on activated charcoal; In tetrahydrofuran; 1,4-dioxane; ethanol; water;
DOI:10.1021/jo00193a016