24277-39-2Relevant articles and documents
Synthesis of novel carboranyl derivatives of α-amino acids
Gruzdev,Levit,Bazhov,Demin,Sadretdinova,Ol'shevskaya,Kalinin,Krasnov,Chupakhina
, p. 110 - 115 (2010)
New routes to closo-carboranyl derivatives of L-lysine and L-glutamic acid with free α-NH2 groups were proposed.
Synthesis and photochemical reactivity of caged glutamates with a π-extended coumarin chromophore as a photolabile protecting group
Sakamoto, Yuya,Boinapally, Srikanth,Katan, Claudine,Abe, Manabu
, p. 7171 - 7174 (2013)
'Caging' and 'uncaging' bioactive substrates are key techniques in studying a wide variety of biological processes. In the present study, two-types of novel caged glutamates with a two-photon absorption (TPA) core, that is, π-extended coumarin, were synthesized and their photochemical release of glutamate was analyzed. The high yields of glutamate (>92%) were observed in the photolysis of compounds 1 and 10, respectively.
Synthesis of ortho-carboranyl derivatives of (S)-asparagine and (S)-glutamine
Gruzdev,Levit,Olshevskaya,Krasnov
, p. 769 - 776 (2017/07/07)
(S)-Asparagine and (S)-glutamine ortho-carboranyl derivatives with free amino and carboxy groups in the α-position were synthesized. By an example of Nγ-(1,2-dicarba-closo-dodecarboran-3-yl)-(S)-glutamine it was demonstrated that the developed synthetic approach carboranyl derivatives of amino acids allowed the preparation of optically pure isomers.
LYSINE ISOTOPOLOGUES, COMPOSITIONS COMPRISING THE SAME AND METHODS OF SYNTHESIS
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, (2016/02/12)
This invention relates to lysine isotopologues of Formulas I and 1-A, as described herein, and processes for synthesizing the same and derivatives and intermediates involved therein. In one aspect, described herein is a chemical compound comprising an isotopically labeled analog, i.e., an isotopologue of a standard or naturally occurring lysine. The lysine isotopologue is synthetically formed to have stable isotopes of elements incorporated at selected positions. As such, the lysine isotopologue has a molecular mass different from the mass of a standard or naturally occurring lysine.