1,5,8-TriMethylcarbazole

Base Information

• Chemical Name: 1,5,8-TriMethylcarbazole
• CAS No.: 78787-83-4
• Molecular Formula: C₁₅H₁₅N
• Molecular Weight: 209.291
• Mol file: 78787-83-4.mol

Synonyms:1,5,8-TriMethylcarbazole;1,4,8-Trimethylcarbazole

Chemical Property of 1,5,8-TriMethylcarbazole

Chemical Property:

• Melting Point: 154-156℃
• Boiling Point: 395.6±11.0 °C(Predicted)
• PKA: 17.90±0.30(Predicted)
• PSA: 15.79000
• Density: 1.132±0.06 g/cm3 (20 oC 760 Torr)
• LogP: 4.24630
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98%Min ^*data from raw suppliers

1,4,8-Trimethyl-9H-carbazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,5,8-TriMethylcarbazole

There total 5 articles about 1,5,8-TriMethylcarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

7-methyl-1H-indole (933-67-5,261352-51-6) + 2,5-hexanedione (110-13-4) → 1,4,8-trimethyl-carbazole (78787-83-4)

Guidance literature:

With toluene-4-sulfonic acid; In ethanol; for 1h; Heating;

Reference yield:

3,2',5'-Trimethyl-2-nitro-biphenyl (108716-17-2) → 1,4,8-trimethyl-carbazole (78787-83-4)

Guidance literature:

With hydrogenchloride; acetic acid; tin(ll) chloride;

Reference yield:

2-iodo-p-xylene (1122-42-5) → 1,4,8-trimethyl-carbazole (78787-83-4)

Guidance literature:

Multi-step reaction with 2 steps

1: copper-powder / 250 - 270 °C

2: tin (II)-chloride; hydrogen chloride; aqueous acetic acid

With hydrogenchloride; copper; acetic acid; tin(ll) chloride;

upstream raw materials:

3,2',5'-Trimethyl-2-nitro-biphenyl

7-methyl-1H-indole

2,5-hexanedione

hydrogenchloride

Refernces