2-fluoro-4-Methoxy-Benzenepropanoic acid

Base Information

Chemical Name:2-fluoro-4-Methoxy-Benzenepropanoic acid
CAS No.:852181-15-8
Molecular Formula:C11H13FO3
Molecular Weight:198.19
Hs Code.:
Mol file:852181-15-8.mol

Synonyms:KLEYADLSRYOXMC-UHFFFAOYSA;RW2702;QC-8941;2-Fluoro-4-methoxybenzenepropanoic acid;

Suppliers and Price of 2-fluoro-4-Methoxy-Benzenepropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(2-fluoro-4-methoxyphenyl)propanoicAcid
10mg
$ 45.00

Crysdot
3-(2-Fluoro-4-methoxyphenyl)propanoicacid 95+%
5g
$ 2126.00

American Custom Chemicals Corporation
3-(2-FLUORO-4-METHOXYPHENYL)PROPANOIC ACID 95.00%
5MG
$ 495.96

AHH
3-(2-FLUORO-4-METHOXYPHENYL)PROPANOICACID 97%
1g
$ 365.00

A1 Biochem Labs
3-(2-Fluoro-4-methoxyphenyl)propanoicacid 95%
5 g
$ 950.00

Total 6 raw suppliers

Chemical Property of 2-fluoro-4-Methoxy-Benzenepropanoic acid

Chemical Property:

Melting Point:86-87℃
PSA：46.53000
Density:1.226±0.06 g/cm3 (20 oC 760 Torr)
LogP:1.85150

Purity/Quality:

99%+ ^*data from raw suppliers

3-(2-fluoro-4-methoxyphenyl)propanoicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-fluoro-4-Methoxy-Benzenepropanoic acid

There total 4 articles about 2-fluoro-4-Methoxy-Benzenepropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 852181-15-8
3-(2-fluoro-4-methoxyphenyl)propionic acid

Guidance literature:: With 4-t-butylbenzenethiol; sodium t-butanolate; In 1-methyl-pyrrolidin-2-one; tert-butyl alcohol; at 25 ℃; for 24h; under 760.051 Torr; Schlenk technique; Sealed tube; Irradiation;

Reference yield:

: 331-64-6
2-fluoro-4-methoxy-benzaldehyde

: 852181-15-8
3-(2-fluoro-4-methoxyphenyl)propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: NaH / dimethylformamide / 0.58 h / 0 - 20 °C

1.2: 75 percent / dimethylformamide / 20 h / 20 °C

2.1: H₂ / Pd/C / methanol / 20 h

3.1: 8.2 g / aq. NaOH / 3 h / Heating

With sodium hydroxide; hydrogen; sodium hydride; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; 1.2: Horner-Emmons reaction;
DOI:10.3390/90600449

Reference yield:

: 852181-14-7
3-(2-fluoro-4-methoxyphenyl)acrylic acid methyl ester

: 852181-15-8
3-(2-fluoro-4-methoxyphenyl)propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C / methanol / 20 h

2: 8.2 g / aq. NaOH / 3 h / Heating

With sodium hydroxide; hydrogen; palladium on activated charcoal; In methanol;
DOI:10.3390/90600449