2-Bromo-4,6-diphenylpyrimidine

Base Information

• Chemical Name: 2-Bromo-4,6-diphenylpyrimidine
• CAS No.: 56181-49-8
• Molecular Formula: C16H11BrN2
• Molecular Weight: 311.181
• Hs Code.: 2933599090
• European Community (EC) Number: 810-948-4
• DSSTox Substance ID: DTXSID401306730
• Mol file: 56181-49-8.mol

Synonyms:2-bromo-4,6-diphenylpyrimidine;56181-49-8;SCHEMBL4893598;DTXSID401306730;AMY37857;MFCD00234884;AKOS022186551;SB67035;AS-40167;B4662;CS-0168407;AC-907/25005296

Chemical Property of 2-Bromo-4,6-diphenylpyrimidine

Chemical Property:

• Melting Point: 127.0 to 131.0 °C
• PSA: 25.78000
• LogP: 4.57310
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 310.01056
• Heavy Atom Count: 19
• Complexity: 246

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Bromo-4,6-diphenylpyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC(=NC(=N2)Br)C3=CC=CC=C3

Technology Process of 2-Bromo-4,6-diphenylpyrimidine

There total 2 articles about 2-Bromo-4,6-diphenylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

2-amino-4,6-diphenylpyrimidine (40230-24-8) → 2-bromo-4,6-diphenyl-pyrimidine (56181-49-8)

Guidance literature:

With hydrogen bromide; bromine; sodium nitrite; In water; at -20 - 20 ℃; for 3h;

Reference yield:

→ 2-bromo-4,6-diphenyl-pyrimidine (56181-49-8)

Guidance literature:

Reference yield: 96.0%

C35H28BNO2 + 2-bromo-4,6-diphenyl-pyrimidine (56181-49-8) → C45H27N3

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; at 120 ℃; for 12h;

upstream raw materials:

2-amino-4,6-diphenylpyrimidine

Downstream raw materials:

4,4',6,6'-tetraphenyl-2,2'-bipyrimidine

Refernces

• 1、 -. "CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE INCLUDING THE CONDENSED-CYCLIC COMPOUND". Page/Page column. . Retrieved 2014/04/03.