Di-t-butyl(3-sulfonatopropyl)phosphine, min. 98%

Base Information

• Chemical Name: Di-t-butyl(3-sulfonatopropyl)phosphine, min. 98%
• CAS No.: 1055888-89-5
• Molecular Formula: (C4H9)2PCH2 CH2CH2SO3H
• Molecular Weight: 268.357
• Mol file: 1055888-89-5.mol

Synonyms:Di-t-butyl(3-sulfonatopropyl)phosphine;

Chemical Property of Di-t-butyl(3-sulfonatopropyl)phosphine, min. 98%

Chemical Property:

• PKA: 1.79±0.50(Predicted)
• PSA: 76.34000
• LogP: 4.42400
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Sensitive.: Air & Moisture Sensitive
• Water Solubility.: Slightly soluble in water.

Purity/Quality:

97% ^*data from raw suppliers

Di-t-butyl(3-sulfonatopropyl)phosphine ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Air stable, water soluble phosphine ligand used in palladium catalyzed cross-coupling reactions

Technology Process of Di-t-butyl(3-sulfonatopropyl)phosphine, min. 98%

There total 1 articles about Di-t-butyl(3-sulfonatopropyl)phosphine, min. 98% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

1,3-propanesultone (1120-71-4) + di-tert-butylphosphine (819-19-2) → 3-(di-tert-butylphosphino)-propane-1-sulfonic acid (1055888-89-5)

Guidance literature:

In 1,4-dioxane; for 12h; Inert atmosphere; Reflux;

DOI:10.1021/ja9084397

upstream raw materials:

1,3-propanesultone

di-tert-butylphosphine

Refernces

• 1、 Brown, William S.,Boykin, D'Ariel D.,M. Quentin Sonnier Jr.,William D. Clark,Brown, Fallon V.,Shaughnessy, Kevin H.. "Sterically demanding, zwitterionic trialkylphosphonium sulfonates as air-stable ligand precursors for efficient palladium-catalyzed cross-couplings of aryl bromides and chlorides". . p. 1965 - 1970. Retrieved 2008.