5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Base Information

Chemical Name:5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one
CAS No.:153873-96-2
Molecular Formula:C15H10BrFN2O
Molecular Weight:333.16
Hs Code.:
ChEMBL ID:CHEMBL5204007
DSSTox Substance ID:DTXSID601342588
Wikidata:Q108452267
Mol file:153873-96-2.mol

Synonyms:153873-96-2;5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one;Flubromazepam Isomer;SCHEMBL7276871;CHEMBL5204007;APTIFBSTEIXFOB-UHFFFAOYSA-N;DTXSID601342588;5-(2-bromophenyl)-7-fluoro-1,3-dihydro-1,4-benzodiazepine-2 (2H)-one;5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (Flubromazepam Isomer);5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one (Flubromazepam Isomer) 1.0 mg/ml in Methanol

Suppliers and Price of 5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:331.99605
Heavy Atom Count:20
Complexity:415

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1C(=O)NC2=C(C=C(C=C2)F)C(=N1)C3=CC=CC=C3Br

Technology Process of 5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one

There total 7 articles about 5-(2-Bromophenyl)-7-fluoro-1,3-dihydro-2H-1,4-benzodiazepin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 2-bromo-N-[2-(2-bromobenzoyl)-4-fluorophenyl]acetamide

: 153873-96-2
5-(2-bromophenyl)-7-fluoro-1,3-dihydro-1,4-benzodiazepine-2-one

Guidance literature:: 2-bromo-N-[2-(2-bromobenzoyl)-4-fluorophenyl]acetamide; With ammonia; In methanol; dichloromethane; at 20 ℃; for 1h;

With acetic acid; In ethanol; for 3h; Reflux;
DOI:10.1016/j.ejmech.2021.114060