Episilvestrol

Base Information

• Chemical Name: Episilvestrol
• CAS No.: 697235-39-5
• Molecular Formula: C34H38O13
• Molecular Weight: 654.668
• Mol file: 697235-39-5.mol

Synonyms:2''-Episilvestrol;CS-0743;5'''-episilvestrol;Episilvestrol;

Chemical Property of Episilvestrol

Chemical Property:

• PSA: 171.83000
• LogP: 1.57280

Purity/Quality:

99% ^*data from raw suppliers

Episilvestrol 99.86% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Episilvestrol

There total 3 articles about Episilvestrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C46H66O13Si2 (960505-99-1) → 5'''-episilvestrol (697235-39-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 1h;

Reference yield: 73.0%

C48H44N2O19 → 5'''-episilvestrol (697235-39-5)

Guidance literature:

C₄₈H₄₄N₂O₁₉; With methanol; sodium methylate; at 20 ℃; for 1h;

With Amberlite; In methanol; pH=7;

Reference yield:

C41H44O13 → (1R,2S,3S,3aR,8aS)-6-{(2S,3R,6R)-6-[(S)-1,2-dihydroxy-ethyl]-3-methoxy-[1,4]dioxan-2-yloxy}-3,3a-dihydroxy-4-methoxy-8a-(4-methoxy-phenyl)-1-phenyl-2,3,3a,8a-tetrahydro-1H-8-oxa-cyclopenta[a]indene-2-carboxylic acid methyl ester + 5'''-episilvestrol (697235-39-5)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; for 3h;

upstream raw materials:

C₄₆H₆₆O₁₃Si₂

Downstream raw materials:

episilvesteric acid

C₃₄H₃₉NO₁₂

C₃₆H₃₉NO₁₂

C₅₆H₇₅N₇O₁₇S

Refernces

• 1、 El Sous, Mariana,Khoo, Mui Ling,Holloway, Georgina,Owen, David,Scammells, Peter J.,Rizzacasa, Mark A.. "Total synthesis of (-)-episilvestrol and (-)-silvestrol". . p. 7835 - 7838. Retrieved 2008/09/18.