Chemical Property of 5-Aminoindole
Chemical Property:
- Appearance/Colour:Grey Crystals
- Vapor Pressure:3.46E-05mmHg at 25°C
- Melting Point:131-133 °C (dec.)(lit.)
- Refractive Index:1.757
- Boiling Point:354 °C at 760 mmHg
- PKA:17.39±0.30(Predicted)
- Flash Point:195 °C
- PSA：41.81000
- Density:1.268 g/cm3
- LogP:2.33130
- Storage Temp.:0-6°C
- Sensitive.:Air & Light Sensitive
- Solubility.:DMSO, Methanol
- Water Solubility.:insoluble
- XLogP3:0.7
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:0
- Exact Mass:132.068748264
- Heavy Atom Count:10
- Complexity:124
- Purity/Quality:
-
99% *data from raw suppliers
5-Aminoindole *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xn,
Xi
- Hazard Codes:Xn,Xi
- Statements:
22-36/37/38-68
- Safety Statements:
26-45-36/37
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=CC2=C(C=CN2)C=C1N
-
Uses
Reactant for preparation of:Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAPCytotoxic and antimitotic agentsInsulin-like growth factor 1 receptor inhibitorsAntitumoral agentsFactor Xa inhibitorPotential antivascular agentsGli1-mediated transcription in the Hedgehog pathwayInhibitors of receptor tyrosine kinase with antiangiogenic effectsPKCθ inhibitorsHIV protease inhibitors 5-Aminoindole functions as a ligand for hydrophobic charge induction chromatography. A reagent for synthetic elaboration.
