2-(2,3-dihydrobenzofuran-6-yl)acetic Acid

Base Information

Chemical Name:2-(2,3-dihydrobenzofuran-6-yl)acetic Acid
CAS No.:152148-70-4
Molecular Formula:C10H10O3
Molecular Weight:178.18
Hs Code.:2932999099
DSSTox Substance ID:DTXSID10441682
Wikidata:Q82258554
Mol file:152148-70-4.mol

Synonyms:2-(2,3-dihydrobenzofuran-6-yl)acetic Acid;152148-70-4;2-(2,3-dihydro-1-benzofuran-6-yl)acetic acid;SCHEMBL1669323;AMY4277;DTXSID10441682;CGA14870;STL373029;AKOS015955953;CS-W006869;2,3-dihydro-1-benzofuran-6-ylacetic acid;2-(2,3-dihydrobenzofuran-6-yl)aceticAcid;2-(2,3-Dihydrobenzo[b]furan-6-yl)acetic acid;EN300-302074;A884038

Suppliers and Price of 2-(2,3-dihydrobenzofuran-6-yl)acetic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
2-(2,3-dihydrobenzofuran-6-yl)aceticacid 96%
1g
$ 636.00

American Custom Chemicals Corporation
2-(2,3-DIHYDROBENZOFURAN-6-YL)ACETIC ACID 95.00%
5MG
$ 496.67

Alichem
2-(2,3-Dihydrobenzofuran-6-yl)aceticacid
1g
$ 727.60

AK Scientific
2-(2,3-Dihydrobenzofuran-6-yl)aceticacid
1g
$ 957.00

Total 17 raw suppliers

Chemical Property of 2-(2,3-dihydrobenzofuran-6-yl)acetic Acid

Chemical Property:

Boiling Point:347.9±11.0 °C(Predicted)
PKA:4.28±0.10(Predicted)
PSA：46.53000
Density:1.300±0.06 g/cm3(Predicted)
LogP:1.24860
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:178.062994177
Heavy Atom Count:13
Complexity:202

Purity/Quality:

97% ^*data from raw suppliers

2-(2,3-dihydrobenzofuran-6-yl)aceticacid 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C1C=CC(=C2)CC(=O)O

Technology Process of 2-(2,3-dihydrobenzofuran-6-yl)acetic Acid

There total 6 articles about 2-(2,3-dihydrobenzofuran-6-yl)acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 152148-65-7
2-(benzofuran-6-yl)acetic acid

: 152148-70-4
2-(2,3-dihydrobenzofuran-6-yl)acetic acid

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; under 1520.1 Torr;

Reference yield:

: 621-37-4
m-hydroxyphenylacetic acid

: 152148-70-4
2-(2,3-dihydrobenzofuran-6-yl)acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / H₂SO₄ / 5 h / Heating

2: 1.) NaH / 1.) DMF, 2.) DMF

3: 1.) PPA, 2.) 1M aq. NaOH / 1.) toluene, 110 deg C, 12 h

4: H₂ / 10percent Pd/C / 760 Torr / Ambient temperature

With sodium hydroxide; sulfuric acid; hydrogen; sodium hydride; palladium on activated charcoal;
DOI:10.1021/jm960723m

Reference yield:

: 22446-38-4
ethyl 3-hydroxyphenylacetate

: 152148-70-4
2-(2,3-dihydrobenzofuran-6-yl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) DMF, 2.) DMF

2: 1.) PPA, 2.) 1M aq. NaOH / 1.) toluene, 110 deg C, 12 h

3: H₂ / 10percent Pd/C / 760 Torr / Ambient temperature

With sodium hydroxide; hydrogen; sodium hydride; palladium on activated charcoal;
DOI:10.1021/jm960723m