621-37-4Relevant articles and documents
Palladium-Catalyzed meta-Selective C-H Alkenylation and Acetoxylation of Arylacetic Acid Using a Pyrimidine Template
Jiao, Bo,Peng, Zhen,Dai, Zhen-Hua,Li, Lei,Wang, He,Zhou, Ming-Dong
, p. 3195 - 3202 (2019)
Palladium-catalyzed remote meta-selective C-H functionalization of arylacetic acid has been developed using a pyrimidine template. This transformation is not only tolerated to a diverse range of arylacetic acid and alkene substrates but also applicable to the synthesis of pharmaceutically active ibuprofen derivatives. Moreover, the pyrimidine template was readily removable and recyclable under mild conditions.
Tuning the redox potential of Ag?Ag2O/WO3 and Ag?Ag2S/WO3 photocatalysts toward diclofenac oxidation and nitrophenol reduction
Ismail, Eman H.,Khalil, Mostafa M. H.,Mohamed, Mohamed Mokhtar,Torad, Eman
, (2021/01/05)
WO3 nanoplates modified with either Ag2O or Ag2S nano-architectures were synthesized by a deposition-hydrothermal route (180 °C for 5 h). They were characterized using X-ray powder diffraction, N2 sorptiometry, Transmission electron microscopy, UV–vis diffuse reflectance spectroscopy, Photoluminescence spectroscopy, and X-ray photoelectron spectroscopy. The photo-catalytic (λ > 420 nm, 160 W) degradation of Diclofenac (DCF; 60 mg/l), was achieved using H2O2 (1 × 10?4 M) with either Ag?Ag2O/WO3 (K = 32.0 × 10-3 min-1) or Ag?Ag2S/WO3 (K = 7.3 × 10-3 min-1) catalysts. In the case of DCF degradation using radical scavengers, [rad]O2? played a key role in the degradation process whilst [rad]OH and holes acted moderately minor roles. The possible DCF degradation paths and intermediates were assessed by LC–MS. Both Ag?Ag2O/WO3 and Ag?Ag2S/WO3 catalysts were used in the photo-reduction of 4-nitrophenol (4-NP; 1.8 × 10?4 M) to 4-aminophenol (4-AP) with rate constants equal 8.3 x 10?3 min-1 and 1.6 x 10?3 min?1, respectively.
Application of quebrachitol in hydrolysis reaction of copper-catalyzed aryl halide
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Paragraph 0054-0056, (2019/07/16)
The invention belongs to the technical field of drug synthesis, and provides application of quebrachitol in a hydrolysis reaction of a copper-catalyzed aryl halide. According to the hydrolysis reaction, copper serves as a catalyst, quebrachitol serves as a ligand, and the hydrolysis reaction is carried out on the aryl halide. The invention further provides a catalytic system of the hydrolysis reaction of the aryl halide. The reaction system comprises the copper catalyst, the quebrachitol, alkali and water, and the system is environmentally friendly and is suitable for industrial application.
