BENZENE, 1-BROMO-4-CYCLOPENTYL-

Base Information

• Chemical Name: BENZENE, 1-BROMO-4-CYCLOPENTYL-
• CAS No.: 59734-91-7
• Molecular Formula: C11H13 Br
• Molecular Weight: 225.128
• Mol file: 59734-91-7.mol

Synonyms:BENZENE, 1-BROMO-4-CYCLOPENTYL-;1-BroMo-4-cyclopentylbenzene

Chemical Property of BENZENE, 1-BROMO-4-CYCLOPENTYL-

Chemical Property:

• PSA: 0.00000
• LogP: 4.10670

Purity/Quality:

98.5% ^*data from raw suppliers

1-Bromo-4-cyclopentylbenzene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BENZENE, 1-BROMO-4-CYCLOPENTYL-

There total 12 articles about BENZENE, 1-BROMO-4-CYCLOPENTYL- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

4-Bromophenylboronic acid (5467-74-3) + C14H9Cl4NO4 → 1-bromo-4-(cyclopentyl)benzene (59734-91-7)

Guidance literature:

With nickel(II) chloride hexahydrate; triethylamine; 4,4'-di-tert-butyl-2,2'-bipyridine; In 1,4-dioxane; N,N-dimethyl-formamide; at 75 ℃; for 12h; Inert atmosphere;

DOI:10.1002/anie.201605463

Reference yield:

cyclopentylbenzene (700-88-9) → 1-bromo-4-(cyclopentyl)benzene (59734-91-7)

Guidance literature:

With bromine; iodine;

DOI:10.1021/ja01867a600

Reference yield:

1-(4-bromophenyl)cyclopentyl formate → 1-bromo-4-(cyclopentyl)benzene (59734-91-7) + 1-bromo-4-(cyclopent-1-en-1-yl)benzene (6725-74-2)

Guidance literature:

With triethylsilane; C₁₉H₃BF₁₄; In dichloromethane; at 20 ℃; Overall yield = 99 %; Overall yield = 66.9 mg; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201902082

upstream raw materials:

cyclopentylbenzene

bromobenzene

cyclopentene

Cyclopentanol

Downstream raw materials:

para-nitrophenyl bromide

2-(4-cyclopentylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

4-(4-Cyclopentyl-phenyl)-3-hydroxy-buttersaeurenitril

4-Bromobenzoic acid

Refernces

• 1、 Richter, Sven C.,Oestreich, Martin. "Bioinspired Metal-Free Formal Decarbonylation of α-Branched Aliphatic Aldehydes at Ambient Temperature". . p. 8508 - 8512. Retrieved 2019/06/04.