2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline

Base Information

Chemical Name:2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline
CAS No.:500579-04-4
Molecular Formula:C27H35N5
Molecular Weight:429.60
Hs Code.:29349990
NSC Number:136476
DSSTox Substance ID:DTXSID50329591
Nikkaji Number:J2.771.649K
Wikidata:Q27166081
ChEMBL ID:CHEMBL471728
Mol file:500579-04-4.mol

Synonyms:GANT 61;GANT-61;GANT61

Suppliers and Price of 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
GANT 61
10mg
$ 438.00

Usbiological
GANT61
1mg
$ 282.00

TRC
GANT61
100mg
$ 875.00

Tocris
GANT61 ≥98%(HPLC)
50
$ 774.00

Tocris
GANT61 ≥98%(HPLC)
10
$ 184.00

Sigma-Aldrich
GANT61 ≥98% (HPLC)
5mg
$ 157.00

Sigma-Aldrich
InSolution? Hh/Gli Antagonist, GANT61
2mg
$ 92.60

Sigma-Aldrich
GANT61 ≥98% (HPLC)
25mg
$ 614.00

Medical Isotopes, Inc.
GANT61
50 mg
$ 1050.00

Matrix Scientific
2,2'-((2-(Pyridin-4-yl)dihydropyrimidine-1,3(2H,4H)-diyl)bis(methylene))bis(N,N-dimethylaniline) 97%
100mg
$ 720.00

Total 35 raw suppliers

Chemical Property of 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline

Chemical Property:

Boiling Point:548.999 °C at 760 mmHg
PKA:5.97±0.10(Predicted)
Flash Point:285.825 °C
PSA：25.85000
Density:1.135 g/cm³
LogP:4.49610
Storage Temp.:Store at -20°C
Solubility.:DMSO: >2mg/mL
XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:429.28924614
Heavy Atom Count:32
Complexity:508

Purity/Quality:

99% ^*data from raw suppliers

GANT 61 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=CC=CC=C1CN2CCCN(C2C3=CC=NC=C3)CC4=CC=CC=C4N(C)C
Uses GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.

Technology Process of 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline

There total 1 articles about 2-[[3-[[2-(dimethylamino)phenyl]methyl]-2-pyridin-4-yl-1,3-diazinan-1-yl]methyl]-N,N-dimethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%