1-Oxa-6-azaspiro[3.3]heptane oxalate

Base Information

• Chemical Name: 1-Oxa-6-azaspiro[3.3]heptane oxalate
• CAS No.: 936947-34-1
• Molecular Formula: C7H11NO5
• Molecular Weight: 99.1326
• Hs Code.: 2934999090
• Mol file: 936947-34-1.mol

Synonyms:1-Oxa-6-azaspiro[3.3]heptane oxalate;1-Oxa-6-azaspiro[3.3]hept...;1-Oxa-6-azaspiro[3.3]heptane heMioxalate;1-Oxa-6-azaspiro[3.3]heptane

Chemical Property of 1-Oxa-6-azaspiro[3.3]heptane oxalate

Chemical Property:

• Boiling Point: 164.1±15.0 °C(Predicted)
• PKA: 9.42±0.20(Predicted)
• PSA: 21.26000
• Density: 1.12±0.1 g/cm3(Predicted)
• LogP: 0.07750
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

1-Oxa-6-azaspiro[3.3]heptane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Oxa-6-azaspiro[3.3]heptane oxalate

There total 2 articles about 1-Oxa-6-azaspiro[3.3]heptane oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H15NO3 (1527518-91-7) → 1-oxa-6-azaspiro[3.3]-heptane (936947-34-1)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 60 ℃; for 72h; under 2585.81 Torr;

Reference yield:

tert-butyl 1-oxa-6-azaspiro[3.3]heptane-6-carboxylate (1223573-41-8) → 1-oxa-6-azaspiro[3.3]-heptane (936947-34-1)

Guidance literature:

With trifluoroacetic acid; In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran;

Reference yield:

1-oxa-6-azaspiro[3.3]-heptane (936947-34-1) + 4-Fluoronitrobenzene (350-46-9,178603-76-4) → C11H12N2O3 (1527518-94-0)

Guidance literature:

With potassium carbonate; In tetrahydrofuran; at 80 ℃; for 5h;

upstream raw materials:

C₁₃H₁₅NO₃

tert-butyl 1-oxa-6-azaspiro[3.3]heptane-6-carboxylate

Downstream raw materials:

C₂₂H₂₂ClFN₄O₃

C₂₃H₂₄ClFN₄O₃

C₁₁H₁₂N₂O₃

4-(2-((4-(1-oxa-6-azaspiro[3.3]heptan-6-yl)phenyl)amino)pyrimidin-4-yl)-N-(cyanomethyl)benzamide