Tert-butyl (6-aminospiro[3.3]heptan-2-YL)carbamate

Base Information

Chemical Name:Tert-butyl (6-aminospiro[3.3]heptan-2-YL)carbamate
CAS No.:1239589-52-6
Molecular Formula:C12H22N2O2
Molecular Weight:226.319
Hs Code.:2924299090
European Community (EC) Number:810-109-2
DSSTox Substance ID:DTXSID90585533
Wikidata:Q72502300
Mol file:1239589-52-6.mol

Synonyms:1239589-52-6;TERT-BUTYL (6-AMINOSPIRO[3.3]HEPTAN-2-YL)CARBAMATE;N-(2-Aminospiro[3.3]hept-6-yl)carbamic acid tert-butyl ester;tert-butyl 6-aminospiro[3.3]hept-2-ylcarbamate;tert-butyl N-{6-aminospiro[3.3]heptan-2-yl}carbamate;MFCD09054707;Carbamic acid, N-(6-aminospiro[3.3]hept-2-yl)-, 1,1-dimethylethyl ester;TERT-BUTYL N-(6-AMINOSPIRO[3.3]HEPTAN-2-YL)CARBAMATE;6-(Boc-amino)spiro[3.3]heptan-2-amine;tert-butyl 6-aminospiro[3.3]heptan-2-ylcarbamate;tert-butyl 6-aminospiro[3...;SCHEMBL15845050;DTXSID90585533;XVXPJMGYUOYFOT-UHFFFAOYSA-N;tert-butyl (Ra)-N-(6-aminospiro[3.3]heptan-2-yl)carbamate;AKOS009132679;PB18965;AS-34084;SY038420;6-(Boc-amino)spiro[3.3]heptane-2-amine;AM20070579;CS-0003949;EN300-29519;E77417;(Ra)-6-Amino-2-(Boc-amino)-spiro[3.3]heptane;J-522870;W-205183;Cis-tert-butyl (6-aminospiro[3.3]heptan-2-yl)carbamate;F8889-1208;Z255149934;TERT-BUTYL(6-AMINOSPIRO[3.3]HEPTAN-2-YL)CARBAMATE;Trans-tert-butyl (6-aminospiro[3.3]heptan-2-yl)carbamate;TERT-BUTYL N-(2-AMINOSPIRO[3.3]HEPTAN-6-YL)CARBAMATE;N-(2-AMINOSPIRO[3.3]HEPT-6-YL)CARBAMIC ACID TERT-BUTYL ESTER 95+%

Suppliers and Price of Tert-butyl (6-aminospiro[3.3]heptan-2-YL)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(2-Aminospiro[3.3]hept-6-yl)carbamicAcidtert-ButylEster
100mg
$ 220.00

Synthonix
N-(2-Aminospiro[3.3]hept-6-yl)carbamicacidtert-butylester 97.0%
500mg
$ 390.00

Synthonix
N-(2-Aminospiro[3.3]hept-6-yl)carbamicacidtert-butylester 97.0%
1g
$ 590.00

Synthonix
N-(2-Aminospiro[3.3]hept-6-yl)carbamicacidtert-butylester 97.0%
5g
$ 1770.00

SynQuest Laboratories
2,6-Diaminospiro[3.3]heptane, 2-Boc protected
1 g
$ 750.00

Matrix Scientific
N-(2-Aminospiro[3.3]hept-6-yl)carbamic acid tert-butyl ester 95%
1g
$ 2823.00

Matrix Scientific
N-(2-Aminospiro[3.3]hept-6-yl)carbamic acid tert-butyl ester 95%
500mg
$ 1750.00

Matrix Scientific
N-(2-Aminospiro[3.3]hept-6-yl)carbamic acid tert-butyl ester 95%
250mg
$ 983.00

Crysdot
tert-Butyl(6-aminospiro[3.3]heptan-2-yl)carbamate 95+%
1g
$ 443.00

Crysdot
tert-Butyl(6-aminospiro[3.3]heptan-2-yl)carbamate 95+%
250mg
$ 197.00

Total 28 raw suppliers

Chemical Property of Tert-butyl (6-aminospiro[3.3]heptan-2-YL)carbamate

Chemical Property:

Melting Point:119℃ (ethanol )
Boiling Point:345.1±41.0 °C(Predicted)
PKA:12.38±0.40(Predicted)
PSA：64.35000
Density:1.09±0.1 g/cm3(Predicted)
LogP:2.87220
Storage Temp.:2-8°C(protect from light)
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:226.168127949
Heavy Atom Count:16
Complexity:282

Purity/Quality:

99%, ^*data from raw suppliers

N-(2-Aminospiro[3.3]hept-6-yl)carbamicAcidtert-ButylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1CC2(C1)CC(C2)N

Technology Process of Tert-butyl (6-aminospiro[3.3]heptan-2-YL)carbamate

There total 2 articles about Tert-butyl (6-aminospiro[3.3]heptan-2-YL)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1239589-51-5
tert-butyl [6-(hydroxyimino)spiro[3.3]hept-2-yl]carbamate

: 1239589-52-6
(6-aminospiro[3.3]hept-2-yl)carbamic acid tert-butyl ester

Guidance literature:: With ammonia; hydrogen; In methanol; for 3h; under 5171.62 Torr;
DOI:10.1021/jo101271h

Reference yield: 79.0%

: 1239589-53-7
C₂₀H₂₈N₂O₄

: 1239589-52-6
(6-aminospiro[3.3]hept-2-yl)carbamic acid tert-butyl ester

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In ethanol; at 45 ℃; for 20h; under 37503.8 - 52505.3 Torr; chemoselective reaction;
DOI:10.1021/jo101271h

Reference yield: 88.0%

: 1239589-52-6
(6-aminospiro[3.3]hept-2-yl)carbamic acid tert-butyl ester

: 122-04-3
4-nitro-benzoyl chloride

: 1239589-56-0
N,N'-spiro[3.3]heptane-2,6-diyl bis(4-nitrobenzamide)

Guidance literature:: (6-aminospiro[3.3]hept-2-yl)carbamic acid tert-butyl ester; With hydrogenchloride; In water; for 0.5h;

4-nitro-benzoyl chloride; With triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 1h;
DOI:10.1021/jo101271h