Benzyl azepan-3-ylcarbaMate

Base Information

Chemical Name:Benzyl azepan-3-ylcarbaMate
CAS No.:1044561-15-0
Molecular Formula:C14H20N2O2
Molecular Weight:248.325
Hs Code.:
Mol file:1044561-15-0.mol

Synonyms:3-Azaspiro[5.5]undecane-3-carboxylic acid,9-oxo-,phenylmethyl ester;Benzyl azepan-3-ylcarbamate;

Suppliers and Price of Benzyl azepan-3-ylcarbaMate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Azepan-3-ol
50mg
$ 155.00

TRC
Azepan-3-ol
10mg
$ 45.00

Total 6 raw suppliers

Chemical Property of Benzyl azepan-3-ylcarbaMate

Chemical Property:

PSA：53.85000
LogP:2.58810

Purity/Quality:

NLT 98% ^*data from raw suppliers

Azepan-3-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzyl azepan-3-ylcarbaMate

There total 3 articles about Benzyl azepan-3-ylcarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108875-45-2
(+/-)-2-oxo-hexahydro-azepin-3-yl]-carbamic acid benzyl ester

: 1044561-15-0
benzyl azepan-3-ylcarbamate

Guidance literature:: (+/-)-2-oxo-hexahydro-azepin-3-yl]-carbamic acid benzyl ester; With borane-THF; In tetrahydrofuran; at 0 - 20 ℃;

With hydrogenchloride; water; In tetrahydrofuran; for 2h; Reflux;

With sodium hydroxide; In water; pH=~ 11;

Reference yield:

: 1044561-17-2
tert-Butyl 3-{[(benzyloxy)carbonyl]amino}azepane-1-carboxylate

: 1044561-15-0
benzyl azepan-3-ylcarbamate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 0 ℃; for 2h;
DOI:10.1039/d0cc02976a

Reference yield:

: 609789-17-5
1-tert-butoxycarbonyl-3-amino-hexahydroazepine

: 501-53-1,94274-21-2
benzyl chloroformate

: 1044561-15-0
benzyl azepan-3-ylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

2: trifluoroacetic acid / dichloromethane / 2 h / 0 °C

With N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In dichloromethane;
DOI:10.1039/d0cc02976a