3,5-Pyridinedicarboxylic acid, 4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-, 3,5-dimethyl ester

Base Information

Chemical Name:3,5-Pyridinedicarboxylic acid, 4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-, 3,5-dimethyl ester
CAS No.:470717-47-6
Molecular Formula:C28H30FNO5
Molecular Weight:479.54
Hs Code.:
Mol file:470717-47-6.mol

Synonyms:3,5-Pyridinedicarboxylic acid, 4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-, 3,5-dimethyl ester;diMethyl 4-(2-(benzyloxy)-4-fluorophenyl)-2,6-diisopropylpyridine-3,5-dicarboxylate

Suppliers and Price of 3,5-Pyridinedicarboxylic acid, 4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-, 3,5-dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
dimethyl4-(2-(benzyloxy)-4-fluorophenyl)-2,6-diisopropylpyridine-3,5-dicarboxylate
1g
$ 1540.00

American Custom Chemicals Corporation
DIMETHYL-4-(2-(BENZYLOXY)-4-FLUOROPHENYL)-2,6-DIISOPROPYLPYRIDINE-3,5-DICARBOXYLATE 95.00%
5MG
$ 498.19

Total 8 raw suppliers

Chemical Property of 3,5-Pyridinedicarboxylic acid, 4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-, 3,5-dimethyl ester

Chemical Property:

Vapor Pressure:7.5E-13mmHg at 25°C
Refractive Index:1.552
Boiling Point:566.5°C at 760 mmHg
Flash Point:296.4°C
PSA：74.72000
Density:1.161g/cm³
LogP:6.28670

Purity/Quality:

NLT 98% ^*data from raw suppliers

dimethyl4-(2-(benzyloxy)-4-fluorophenyl)-2,6-diisopropylpyridine-3,5-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3,5-Pyridinedicarboxylic acid, 4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-, 3,5-dimethyl ester

There total 4 articles about 3,5-Pyridinedicarboxylic acid, 4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-, 3,5-dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: C₁₃H₁₀BrFMgO

: 470717-52-3
dimethyl 2,6-diisopropyl-4-methoxy-3,5-pyridine-dicarboxylate

: 470717-47-6
dimethyl 2,6-diisopropyl-4-(2'-benzyloxy-4'-fluoro-phenyl)-3,5-pyridinedicarboxylate

Guidance literature:: In tetrahydrofuran; Heating;
DOI:10.1016/S0960-894X(02)00143-9 DOI:10.1016/S0960-894X(02)00736-9

Reference yield:

: 1830-54-2
3-oxopentanedioic acid dimethyl ester

: 470717-47-6
dimethyl 2,6-diisopropyl-4-(2'-benzyloxy-4'-fluoro-phenyl)-3,5-pyridinedicarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 64 percent / pyridine / 1,2-dichloro-ethane / 0 °C

2: 92 percent / NH₃ / methanol / 0 °C

3: 95 percent / K₂CO₃ / acetone / Heating

4: 78 percent / tetrahydrofuran / Heating

With pyridine; ammonia; potassium carbonate; In tetrahydrofuran; methanol; 1,2-dichloro-ethane; acetone;
DOI:10.1016/S0960-894X(02)00736-9

Reference yield:

: 470717-48-7
dimethyl 2,6-diisopropyl-4-oxo-2H-pyran-3,5-dicarboxylate

: 470717-47-6
dimethyl 2,6-diisopropyl-4-(2'-benzyloxy-4'-fluoro-phenyl)-3,5-pyridinedicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / NH₃ / methanol / 0 °C

2: 95 percent / K₂CO₃ / acetone / Heating

3: 78 percent / tetrahydrofuran / Heating

With ammonia; potassium carbonate; In tetrahydrofuran; methanol; acetone;
DOI:10.1016/S0960-894X(02)00736-9