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4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide hydrate

Base Information
  • Chemical Name:4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide hydrate
  • CAS No.:1196074-08-4
  • Molecular Formula:C27H33N5O7S
  • Molecular Weight:588.084
  • Hs Code.:
  • Mol file:1196074-08-4.mol
4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide hydrate

Synonyms:3-Buten-2-one,4-[(difluoroboryl)oxy]-4-phenyl;Borsaeuredifluorid-1-phenyl-3-oxo-buten-(1)-yl-ester;bosentan monohydrochloride;

Suppliers and Price of 4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide hydrate
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Chemenu
  • 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2''-bipyrimidin]-4-yl)benzenesulfonamidehydrochloride 95%+
  • 250mg
  • $ 751.00
  • Chemenu
  • 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2''-bipyrimidin]-4-yl)benzenesulfonamidehydrochloride 95%+
  • 100mg
  • $ 451.00
Total 7 raw suppliers
Chemical Property of 4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide hydrate
Chemical Property:
  • PSA:163.26000 
  • LogP:5.29340 
Purity/Quality:

NLT 98% *data from raw suppliers

4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-[2,2''-bipyrimidin]-4-yl)benzenesulfonamidehydrochloride 95%+ *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
Technology Process of 4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide hydrate

There total 2 articles about 4-tert-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide hydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
ethylene glycol; With sodium hydroxide; at 45 - 50 ℃; for 0.5h;
4-(tert-butyl)-N-(6-chloro-5-(2-methoxyphenoxy)-(2,2'-bipyrimidine)-4-yl)benzenesulfonamide sodium salt; In dimethyl sulfoxide; at 40 - 50 ℃; for 4h;
With hydrogenchloride; In water; isopropyl alcohol; at 20 - 30 ℃; for 4h;
Guidance literature:
With hydrogenchloride; In isopropyl alcohol; at 40 ℃; for 2h; Product distribution / selectivity;
Guidance literature:
With sodium hydrogencarbonate; In ethanol; water; for 2h; pH=7;
upstream raw materials:

bosentan

ethylene glycol

Downstream raw materials:

bosentan

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