1,1'-Spirobi[1H-indene]-5,5',6,6'-tetrol, 2,2',3,3'-tetrahydro-3,3,3',3'-tetramethyl-

Base Information

• Chemical Name: 1,1'-Spirobi[1H-indene]-5,5',6,6'-tetrol, 2,2',3,3'-tetrahydro-3,3,3',3'-tetramethyl-
• CAS No.: 77-08-7
• Deprecated CAS: 122465-36-5,163385-89-5,1010693-29-4,163385-89-5
• Molecular Formula: C21H24O4
• Molecular Weight: 340.419
• Hs Code.: 2932990090
• European Community (EC) Number: 201-003-1
• NSC Number: 512922,82063
• UNII: JQV6E6TUQ7
• DSSTox Substance ID: DTXSID5058806
• Nikkaji Number: J56.213K
• Wikidata: Q2406742
• ChEMBL ID: CHEMBL304266
• Mol file: 77-08-7.mol

Synonyms:3,3,3',3'-tetramethyl-1,1'-spirobi(indan)-5,5',6,6'-tetrol;4Me4OH-spirobi(indan)

Chemical Property of 1,1'-Spirobi[1H-indene]-5,5',6,6'-tetrol, 2,2',3,3'-tetrahydro-3,3,3',3'-tetramethyl-

Chemical Property:

• Melting Point: 300 °C
• Boiling Point: 561.2 °C at 760 mmHg
• PKA: 9.81±0.60(Predicted)
• Flash Point: 260.8 °C
• PSA: 80.92000
• Density: 1.37 g/cm³
• LogP: 4.15770
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility.: Slightly soluble in methanol.
• XLogP3: 5.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 340.16745924
• Heavy Atom Count: 25
• Complexity: 494

Purity/Quality:

99.9% ^*data from raw suppliers

5,5',6,6'-Tetrahydroxy-3,3,3',3'-tetramethyl-1,1'-spirobiindane >96.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1(CC2(CC(C3=CC(=C(C=C32)O)O)(C)C)C4=CC(=C(C=C41)O)O)C
• Uses: 5,5',6,6'-Tetrahydroxy-3,3,3',3'- tetramethyl-1,1'-spirobisindane is used in the preparation of 4,7,4',7'-tetrabromo-3,3,3',3'-tetramethyl-2,3,2',3'-tetrahydro-[1,1']spirobiindene-5,6,5',6'-tetraol by bromination using bromine.

Technology Process of 1,1'-Spirobi[1H-indene]-5,5',6,6'-tetrol, 2,2',3,3'-tetrahydro-3,3,3',3'-tetramethyl-

There total 5 articles about 1,1'-Spirobi[1H-indene]-5,5',6,6'-tetrol, 2,2',3,3'-tetrahydro-3,3,3',3'-tetramethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) + acetone (67-64-1) → 3,3,3',3'-tetramethyl-2,3,2',3'-tetrahydro-[1,1']spirobiindene-5,6,5',6'-tetraol (77-08-7)

Guidance literature:

With hydrogen iodide; In acetic acid; for 5h; Heating;

DOI:10.1039/b307270c

Reference yield:

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) + acetic acid (64-19-7,77671-22-8) + acetone (67-64-1) → 3,3,3',3'-tetramethyl-2,3,2',3'-tetrahydro-[1,1']spirobiindene-5,6,5',6'-tetraol (77-08-7)

Guidance literature:

With hydrogen iodide; In water; at 120 ℃; for 10h; Heating;

Reference yield:

4-methyl-pent-3-en-2-one (141-79-7) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 3,3,3',3'-tetramethyl-2,3,2',3'-tetrahydro-[1,1']spirobiindene-5,6,5',6'-tetraol (77-08-7)

Guidance literature:

With hydrogenchloride; acetic acid;

DOI:10.1039/jr9340001681

upstream raw materials:

4-methyl-pent-3-en-2-one

benzene-1,2-diol

phorone

acetone

Downstream raw materials:

4-isopropylcatechol

benzene-1,2-diol

Refernces

• 1、 -. "Polyacid monomer and preparation method thereof, polyamide and preparation method thereof, and polyamide film". Paragraph 0099; 0100. . Retrieved 2019/07/04.
• 2、 Dei, Andrea,Sorace, Lorenzo. "pH-triggered intramolecular electron transfer in asymmetric bis-dioxolene adducts". . p. 3382 - 3386. Retrieved 2007/10/03.