di-tert-butyl 2-Methyl-2-(5-(tosyloxy)pentyl)Malonate

Base Information

• Chemical Name: di-tert-butyl 2-Methyl-2-(5-(tosyloxy)pentyl)Malonate
• CAS No.: 1236354-13-4
• Molecular Formula: C24H38O7S
• Molecular Weight: 470.62
• Mol file: 1236354-13-4.mol

Synonyms:di-tert-butyl 2-Methyl-2-(5-(tosyloxy)pentyl)Malonate;

Chemical Property of di-tert-butyl 2-Methyl-2-(5-(tosyloxy)pentyl)Malonate

Chemical Property:

• Boiling Point: 536.1±45.0 °C(Predicted)
• PSA: 104.35000
• Density: 1.107±0.06 g/cm3(Predicted)
• LogP: 6.03120

Purity/Quality:

98%min ^*data from raw suppliers

di-tert-butyl2-Methyl-2-(5-(tosyloxy)pentyl)Malonate 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of di-tert-butyl 2-Methyl-2-(5-(tosyloxy)pentyl)Malonate

There total 1 articles about di-tert-butyl 2-Methyl-2-(5-(tosyloxy)pentyl)Malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

1,3-di-tert-butyl 2-methylpropanedioate (34812-95-8) + 1,5-bis(p-toluenesulfonyloxy)pentane (24293-28-5) → 2-methyl-2-[5-(toluene-4-sulfonyloxy)-pentyl]-malonic acid di-tert-butyl ester (1236354-13-4)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 50 ℃; for 16h; Product distribution / selectivity; Inert atmosphere;

upstream raw materials:

1,3-di-tert-butyl 2-methylpropanedioate

1,5-bis(p-toluenesulfonyloxy)pentane

Refernces