N-(2-chloroacetyl)-2-methoxybenzamide

Base Information

Chemical Name:N-(2-chloroacetyl)-2-methoxybenzamide
CAS No.:554423-67-5
Molecular Formula:C10H10ClNO3
Molecular Weight:227.64
Hs Code.:
European Community (EC) Number:867-196-5
Mol file:554423-67-5.mol

Synonyms:N-(2-chloroacetyl)-2-methoxybenzamide;554423-67-5;Benzamide, N-(2-chloroacetyl)-2-methoxy-;N-(2-Chloro-acetyl)-2-methoxy-benzamide;CS-M1594;N-2-chloroacetyl-2-methoxybenzamide;AKOS000117674;CS-14408;BenzaMide,N-(2-chloroacetyl)-2-Methoxy-;EN300-05817;SR-01000042905;SR-01000042905-1;Z56912092

Suppliers and Price of N-(2-chloroacetyl)-2-methoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(2-Chloroacetyl)-2-methoxy-benzamide
100mg
$ 90.00

Total 6 raw suppliers

Chemical Property of N-(2-chloroacetyl)-2-methoxybenzamide

Chemical Property:

PSA：55.40000
LogP:1.58130
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:227.0349209
Heavy Atom Count:15
Complexity:245

Purity/Quality:

≥95% ^*data from raw suppliers

N-(2-Chloroacetyl)-2-methoxy-benzamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC=C1C(=O)NC(=O)CCl

Technology Process of N-(2-chloroacetyl)-2-methoxybenzamide

There total 1 articles about N-(2-chloroacetyl)-2-methoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2439-77-2
2-methoxybenzamide

: 79-04-9
chloroacetyl chloride

: 554423-67-5
N-2-chloroacetyl-2-methoxybenzamide

Guidance literature:: at 110 ℃; for 2h;
DOI:10.1021/ja061364f

Reference yield:

: 554423-67-5
N-2-chloroacetyl-2-methoxybenzamide

: (3S)-N-[(8-tert-butyldimethylsilanoyloxy)-3,3-dicyanomethyloctanoyl]-2-methoxybenzamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: 53 h / 80 °C

2.1: n-butyl lithium / hexane; tetrahydrofuran / 0.25 h / -78 °C

2.2: 70 percent / hexane; tetrahydrofuran / 20 °C

3.1: chiral thiourea / toluene / 5 h / 20 °C

With n-butyllithium; chiral thiourea; In tetrahydrofuran; hexane; toluene; 3.1: Michael addition;
DOI:10.1021/ja061364f

Reference yield:

: 554423-67-5
N-2-chloroacetyl-2-methoxybenzamide

: (3S)-8-tert-butyldimethylsilanoyloxy-2-cyano-3-[2-(2-methoxybenzoylamino)-2-oxoethyl]octanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: 53 h / 80 °C

2.1: n-butyl lithium / hexane; tetrahydrofuran / 0.25 h / -78 °C

2.2: 70 percent / hexane; tetrahydrofuran / 20 °C

3.1: chiral thiourea / toluene / 137 h / 20 °C

With n-butyllithium; chiral thiourea; In tetrahydrofuran; hexane; toluene; 3.1: Michael addition;
DOI:10.1021/ja061364f