(1S,2S)-2-((R)-1-phenylethylaMino)cyclohexanol

Base Information

Chemical Name:(1S,2S)-2-((R)-1-phenylethylaMino)cyclohexanol
CAS No.:98361-56-9
Molecular Formula:C14H21NO
Molecular Weight:219.327
Hs Code.:
Mol file:98361-56-9.mol

Synonyms:(1S,2S)-Pseudoephedrine |A-fluoroacetamide;

Suppliers and Price of (1S,2S)-2-((R)-1-phenylethylaMino)cyclohexanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
(1S,2S)-2-((R)-1-phenylethylamino)cyclohexanol >98.0%
250mg
$ 61.00

Total 7 raw suppliers

Chemical Property of (1S,2S)-2-((R)-1-phenylethylaMino)cyclohexanol

Chemical Property:

PSA：32.26000
LogP:3.03160

Purity/Quality:

≥95% ^*data from raw suppliers

(1S,2S)-2-((R)-1-phenylethylamino)cyclohexanol >98.0% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1S,2S)-2-((R)-1-phenylethylaMino)cyclohexanol

There total 1 articles about (1S,2S)-2-((R)-1-phenylethylaMino)cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 3886-69-9
(R)-1-phenyl-ethyl-amine

: 286-20-4
cyclohexane-1,2-epoxide

: 98361-56-9
(1S,2S)-trans-2-[(R)-(α-methylbenzyl)amino]cyclohexanol

: 98462-58-9
(1R,2R)-trans-2-[(R)-(α-methylbenzyl)amino]cyclohexanol

Guidance literature:: (R)-1-phenyl-ethyl-amine; With trimethylaluminum; In hexane; dichloromethane; at 0 ℃; for 1h;

cyclohexane-1,2-epoxide; In dichloromethane; at 0 - 20 ℃; for 21h;
DOI:10.1016/S0957-4166(00)00340-2

Reference yield: 80.0%

: 98361-56-9
(1S,2S)-trans-2-[(R)-(α-methylbenzyl)amino]cyclohexanol

: 931-15-7,931-16-8,6850-38-0,6982-39-4,33092-82-9,38898-70-3,74111-21-0,108267-20-5
(1S,2S)-trans-2-aminocyclohexanol

Guidance literature:: With palladium on activated charcoal; ammonium formate; In methanol; Ambient temperature;
DOI:10.1021/jm970065l

Reference yield:

: 98361-56-9
(1S,2S)-trans-2-[(R)-(α-methylbenzyl)amino]cyclohexanol

: 365996-26-5
(+/-)-cis-N-[(5-Methyl-4,5,6,7-tetrahydrothiazolo-[5,4-c]pyridin-2-yl)carbonyl]-1,2-cyclohexanediamine

Guidance literature:: Multi-step reaction with 7 steps

1: HCOONH₄ / Pd/C / methanol

2: CH₂Cl₂

3: 94 percent / pyridine

4: 47 percent / NaN₃ / dimethylformamide

5: H₂ / Pd/C

6: WSCI; HOBt / dimethylformamide

7: 100 percent / HCl / ethanol

With pyridine; hydrogenchloride; sodium azide; hydrogen; ammonium formate; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; palladium on activated charcoal; In methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2007.05.068