Meayamycin

Base Information

Chemical Name:Meayamycin
CAS No.:933474-26-1
Molecular Formula:C28H43NO7
Molecular Weight:505.64
Hs Code.:

Synonyms:(2Z,4S)-4-(Acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-6-[(2E,4E)-5-[(3R,4R,5R)-4-hydroxy-7,7-dimethyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadien-1-yl]-2,5-dimethyl-2H-pyran-3-yl]-2-pentenamide;2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-6-[(2E,4E)-5-[(3R,4R,5R)-4-hydroxy-7,7-dimethyl-1,6-dioxaspiro[2.5]oct-5-yl]-3-methyl-2,4-pentadien-1-yl]-2,5-dimethyl-2H-pyran-3-yl]-, (2Z,4S)-;

Suppliers and Price of Meayamycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 26 raw suppliers

Chemical Property of Meayamycin

Chemical Property:

PSA：106.62000
LogP:3.77340

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Use Description Meayamycin is a natural product with potential applications in various fields. In the field of cancer research and drug development, meayamycin has gained attention as a potential anti-cancer agent. It is being studied for its ability to inhibit the growth of cancer cells by disrupting specific cellular pathways, making it a candidate for the development of novel cancer therapies. Additionally, in the realm of molecular biology and biochemistry, meayamycin is employed as a research tool to better understand cellular processes and protein interactions. Its unique mechanism of action makes it valuable in studying molecular pathways and identifying potential drug targets. While its applications are primarily in cancer research and molecular biology, meayamycin has the potential to advance our understanding of disease mechanisms and contribute to the development of new treatments in the future.

Technology Process of Meayamycin

There total 36 articles about Meayamycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 882028-31-1
(S,Z)-5-(((2R,3R,5S,6S)-2,5-dimethyl-6-((E)-3-methylpenta-2,4-dien-1-yl)tetrahydro-2H-pyran-3-yl)amino)-5-oxopent-3-en-2-yl acetate

: 933190-01-3
(3R,4R,5R)-7,7-dimethyl-5-vinyl-1,6-dioxaspiro[2.5]octan-4-ol

: 933474-26-1
meayamycin

Guidance literature:: With p-benzoquinone; In 1,2-dichloro-ethane; for 14h;
DOI:10.1021/acs.orglett.0c03308

Reference yield:

: 310397-89-8
(Z)-(4S)-4-acetoxypent-2-enoic acid

: 933474-26-1
meayamycin

Guidance literature:: Multi-step reaction with 4 steps

1: HATU; iPrNEt / acetonitrile / 23 °C

2: 57 percent / 3-nitro-substituted phenylmethylene of Hoveyda catalyst / CH₂Cl₂ / 23 °C

3: 86 percent / KOtBu / tetrahydrofuran / 0 °C

4: 45 percent / benzoquinone; [2-(2-oxopropyl)-oxiranyl]-triethylsilanyloxy-acetaldehyde / 3-nitro-substituted phenylmethylene of Hoveyda catalyst / 1,2-dichloro-ethane / 23 - 40 °C

With [2-(2-oxo-propyl)-oxiranyl]-triethylsilanyloxy-acetaldehyde; potassium tert-butylate; N-isopropylethylamine; p-benzoquinone; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; 3-nitro-substituted phenylmethylene of Hoveyda catalyst; In tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; acetonitrile;
DOI:10.1021/ja067870m

Reference yield:

: 882028-44-6
(2S,3Z)-5-{[(2R,3R,5S,6S)-2,5-dimethyl-6-(prop-2-en-1-yl)tetrahydro-2H-pyran-3-yl]amino}-5-oxopent-3-en-2-yl acetate

: 933474-26-1
meayamycin

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / 3-nitro-substituted phenylmethylene of Hoveyda catalyst / CH₂Cl₂ / 23 °C

2: 86 percent / KOtBu / tetrahydrofuran / 0 °C

3: 45 percent / benzoquinone; [2-(2-oxopropyl)-oxiranyl]-triethylsilanyloxy-acetaldehyde / 3-nitro-substituted phenylmethylene of Hoveyda catalyst / 1,2-dichloro-ethane / 23 - 40 °C

With [2-(2-oxo-propyl)-oxiranyl]-triethylsilanyloxy-acetaldehyde; potassium tert-butylate; p-benzoquinone; 3-nitro-substituted phenylmethylene of Hoveyda catalyst; In tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/ja067870m