Daun02

Base Information

Chemical Name:Daun02
CAS No.:290304-24-4
Molecular Formula:C41H44N2O20
Molecular Weight:884.802
Hs Code.:
Mol file:290304-24-4.mol

Synonyms:Daun02;(8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-(beta-D-galactopyranosyloxy)-3-nitrophenyl]methoxy]carbonyl]amino]-alpha-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione

Suppliers and Price of Daun02

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
Daun02 >98%
250 mg
$ 2700.00

DC Chemicals
Daun02 >98%
100 mg
$ 1350.00

Crysdot
Daun02 98+%
10mg
$ 286.00

Crysdot
Daun02 98+%
5mg
$ 158.00

ChemScene
Daun02 98.85%
5mg
$ 290.00

ChemScene
Daun02 98.85%
2mg
$ 216.00

ChemScene
Daun02 98.85%
10mg
$ 528.00

ApexBio Technology
Daun02
25mg
$ 835.00

ApexBio Technology
Daun02
10mg
$ 499.00

American Custom Chemicals Corporation
DAUN-02 95.00%
5MG
$ 490.60

Total 11 raw suppliers

Chemical Property of Daun02

Chemical Property:

Boiling Point:1128.4±65.0 °C(Predicted)
PKA:7.39±0.60(Predicted)
PSA：346.84000
Density:1.67±0.1 g/cm3(Predicted)
LogP:0.81110
Solubility.:insoluble in H2O; insoluble in EtOH; ≥17.92 mg/mL in DMSO with ultrasonic

Purity/Quality:

97% ^*data from raw suppliers

Daun02 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Daun02

There total 6 articles about Daun02 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 290304-25-5
C₄₉H₅₂N₂O₂₄

: 290304-24-4
[6-(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-carbamic acid 3-nitro-4-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-benzyl ester

Guidance literature:: With sodium methylate; In methanol; at 0 - 5 ℃; for 2.5h;
DOI:10.1016/S0040-4039(00)00742-5

Reference yield:

: 3011-34-5
4-hydroxy-3-nitrobenzaldehyde

: 290304-24-4
[6-(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-carbamic acid 3-nitro-4-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-benzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 69 percent / Ag₂O / acetonitrile / 4 h / 20 °C

2: 73 percent / NaBH₄ / CHCl₃; propan-2-ol / 2 h / 0 - 5 °C

3: acetonitrile / 1.5 h

4: Et₃N / dimethylformamide / 0.42 h / 20 °C

5: 47 percent / MeONa / methanol / 2.5 h / 0 - 5 °C

With sodium tetrahydroborate; sodium methylate; triethylamine; silver(l) oxide; In methanol; chloroform; N,N-dimethyl-formamide; isopropyl alcohol; acetonitrile; 1: Condensation / 2: Reduction / 3: Condensation / 4: Condensation / 5: Deacetylation;
DOI:10.1016/S0040-4039(00)00742-5

Reference yield:

: 121358-46-1,77667-26-6
(2R,3S,4S,5R,6S)-2-(acetoxymethyl)-6-(4-formyl-2-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate

: 290304-24-4
[6-(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-carbamic acid 3-nitro-4-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 73 percent / NaBH₄ / CHCl₃; propan-2-ol / 2 h / 0 - 5 °C

2: acetonitrile / 1.5 h

3: Et₃N / dimethylformamide / 0.42 h / 20 °C

4: 47 percent / MeONa / methanol / 2.5 h / 0 - 5 °C

With sodium tetrahydroborate; sodium methylate; triethylamine; In methanol; chloroform; N,N-dimethyl-formamide; isopropyl alcohol; acetonitrile; 1: Reduction / 2: Condensation / 3: Condensation / 4: Deacetylation;
DOI:10.1016/S0040-4039(00)00742-5