Nvp-lcq195

Base Information

Chemical Name:Nvp-lcq195
CAS No.:902156-99-4
Molecular Formula:C17H19Cl2N5O4S
Molecular Weight:460.341
Hs Code.:
DSSTox Substance ID:DTXSID90470112
Wikidata:Q82298097
Mol file:902156-99-4.mol

Synonyms:NVP-LCQ195;902156-99-4;LCQ-195;4-[(2,6-dichlorobenzoyl)amino]-N-(1-methylsulfonylpiperidin-4-yl)-1H-pyrazole-5-carboxamide;C17H19Cl2N5O4S;SCHEMBL2029686;SCHEMBL17252164;DTXSID90470112;CCUXEBOOTMDSAM-UHFFFAOYSA-N;CLB15699;AT9311;AKOS037645025;AT-9311;CS-0840;NCGC00379060-01;NCGC00379060-02;AS-56236;HY-15241;F80343;4-(2,6-dichlorobenzamido)-N-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazole-3-carboxamide;4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulfonyl-piperidin-4-yl)-amide;4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide;4-(2,6-DICHLOROBENZAMIDO)-N-(1-METHANESULFONYLPIPERIDIN-4-YL)-1H-PYRAZOLE-3-CARBOXAMIDE;4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide

Suppliers and Price of Nvp-lcq195

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

DC Chemicals
NVP-LCQ195 >98%
1 g
$ 2600.00

DC Chemicals
NVP-LCQ195 >98%
250 mg
$ 1300.00

DC Chemicals
NVP-LCQ195 >98%
100 mg
$ 700.00

Crysdot
NVP-LCQ195 98+%
5mg
$ 166.00

Crysdot
NVP-LCQ195 98+%
10mg
$ 233.00

ChemScene
NVP-LCQ195 99.80%
10mg
$ 330.00

ChemScene
NVP-LCQ195 99.80%
5mg
$ 230.00

Chemenu
4-(2,6-dichlorobenzamido)-N-(1-(methylsulfonyl)piperidin-4-yl)-1H-pyrazole-3-carboxamide 98%
10mg
$ 218.00

ApexBio Technology
NVP-LCQ195
10mg
$ 359.00

ApexBio Technology
NVP-LCQ195
5mg
$ 256.00

Total 10 raw suppliers

Chemical Property of Nvp-lcq195

Chemical Property:

PKA:11.10±0.70(Predicted)
PSA：136.13000
Density:1.57±0.1 g/cm3(Predicted)
LogP:3.91620
Solubility.:insoluble in H2O; ≥152.4 mg/mL in DMSO; ≥3.28 mg/mL in EtOH with gentle warming and ultrasonic
XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:459.0534807
Heavy Atom Count:29
Complexity:701

Purity/Quality:

99%, ^*data from raw suppliers

NVP-LCQ195 >98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)N1CCC(CC1)NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl

Technology Process of Nvp-lcq195

There total 11 articles about Nvp-lcq195 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.7%

: 124-63-0
methanesulfonyl chloride

: 902156-99-4
4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide

Guidance literature:: 4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-yl-amide methanesulphonic salt; With methanesulfonic acid; In water; at 95 - 105 ℃; for 1.33333 - 1.66667h;

methanesulfonyl chloride; With sodium hydrogencarbonate; In water; ethyl acetate; at 15 - 25 ℃; for 2.5 - 3.75h;

Reference yield: 90.7%

: 4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-yl-amide methanesulphonic salt

: 124-63-0
methanesulfonyl chloride

: 902156-99-4
4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide

Guidance literature:: 4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-yl-amide methanesulphonic salt; With methanesulfonic acid; In water; at 15 - 105 ℃; for 1.33333 - 1.66667h; Industry scale;

With sodium hydrogencarbonate; In water; at 15 - 25 ℃;

methanesulfonyl chloride; In water; at 15 - 25 ℃; for 2.5 - 3.75h; Product distribution / selectivity;

Reference yield: 82.3%

: 902156-99-4
4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid (1-methanesulphonyl-piperidin-4-yl)-amide

Guidance literature:: In ISOPROPYLAMIDE; acetone; at 40 - 80 ℃; Industry scale;

In ISOPROPYLAMIDE; water; acetone; at 15 - 80 ℃; for 14 - 24h; Heating / reflux;

In water; at 15 - 25 ℃; for 0.5 - 0.666667h; Purification / work up;