Technology Process of CIS-3-AMINO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID
There total 7 articles about CIS-3-AMINO-TETRAHYDROPYRAN-4-CARBOXYLIC ACID which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
1,4-dioxane;
at 0 - 20 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: hydroxylamine hydrochloride / water; ethanol / 12 h / 70 °C
2: sodium hypochlorite; triethanolamine / dichloromethane / 12 h / 0 - 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 12 h / 90 °C
4: pyridine; sodium carbonate / dichloromethane / 12 h / 20 °C
5: sodium periodate; ruthenium trichloride / water; acetonitrile; tetrachloromethane / 0 - 20 °C
6: (S)-1-phenyl-ethylamine / acetonitrile / 12 h / 40 - 82 °C
7: hydrogenchloride / 1,4-dioxane / 1 h / 0 - 20 °C
With
pyridine; hydrogenchloride; ruthenium trichloride; sodium hypochlorite; sodium periodate; lithium aluminium tetrahydride; triethanolamine; (S)-1-phenyl-ethylamine; hydroxylamine hydrochloride; sodium carbonate;
In
tetrahydrofuran; 1,4-dioxane; tetrachloromethane; ethanol; dichloromethane; water; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: (S)-1-phenyl-ethylamine / acetonitrile / 12 h / 40 - 82 °C
2: hydrogenchloride / 1,4-dioxane / 1 h / 0 - 20 °C
With
hydrogenchloride; (S)-1-phenyl-ethylamine;
In
1,4-dioxane; acetonitrile;
