1,2,3,4-Tetrahydro-1,4-methano-naphthalene-2,3-diol

Base Information

Chemical Name:1,2,3,4-Tetrahydro-1,4-methano-naphthalene-2,3-diol
CAS No.:26326-70-5
Molecular Formula:C₁₁H₁₂O₂
Molecular Weight:176.215
Hs Code.:

Synonyms:1,2,3,4-Tetrahydro-1,4-methano-naphthalene-2,3-diol;1,4-Methanonaphthalene-2,3-diol, 1,2,3,4-tetrahydro-, (1R,2R,3S,4S)-rel-

Suppliers and Price of 1,2,3,4-Tetrahydro-1,4-methano-naphthalene-2,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydro-1,4-methano-naphthalene-2,3-diol

Chemical Property:

PSA：40.46000
LogP:0.99290

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1,2,3,4-Tetrahydro-1,4-methano-naphthalene-2,3-diol

There total 5 articles about 1,2,3,4-Tetrahydro-1,4-methano-naphthalene-2,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 4453-90-1
1,4-dihydro-1,4-methanonaphthalene

: 26326-70-5
(1R,2R,3S,4S)-1,2,3,4-tetrahydro-1,4-methanonaphthalene-2,3-diol

Guidance literature:: With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In acetone; tert-butyl alcohol; for 60h;
DOI:10.1055/s-2004-829135

Reference yield: 70.0%

: 4453-90-1
1,4-dihydro-1,4-methanonaphthalene

: 26326-70-5
(1R,2R,3S,4S)-1,2,3,4-tetrahydro-1,4-methanonaphthalene-2,3-diol

Guidance literature:: With 4-methylmorpholine N-oxide; In water; tert-butyl alcohol; at 60 ℃; Inert atmosphere;

Reference yield:

: 542-92-7,25568-84-7,7313-32-8
cyclopenta-1,3-diene

: 26326-70-5
(1R,2R,3S,4S)-1,2,3,4-tetrahydro-1,4-methanonaphthalene-2,3-diol

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / n-BuLi / toluene; hexane / 20 °C

2: 89 percent / aq. OsO₄; N-methylmorpholine-N-oxide / acetone; 2-methyl-propan-2-ol / 60 h

With osmium(VIII) oxide; n-butyllithium; 4-methylmorpholine N-oxide; In hexane; acetone; toluene; tert-butyl alcohol;
DOI:10.1055/s-2004-829135