ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate

Base Information

• Chemical Name: ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate
• CAS No.: 31686-94-9
• Molecular Formula: C12H11FO4
• Molecular Weight: 238.215
• Hs Code.: 2918300090
• Mol file: 31686-94-9.mol

Synonyms:Benzenebutanoic acid, 4-fluoro-.alpha.,.gaMMa.-dioxo-, ethyl ester;

Chemical Property of ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate

Chemical Property:

• Boiling Point: 360.9±22.0 °C(Predicted)
• PKA: 6.00±0.25(Predicted)
• PSA: 60.44000
• Density: 1.241±0.06 g/cm3(Predicted)
• LogP: 1.53070
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate

There total 2 articles about ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate (31686-94-9)

Guidance literature:

Reference yield: 96.0%

1-(4-fluorophenyl)ethanone (403-42-9) + oxalic acid diethyl ester (95-92-1) → ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate (31686-94-9)

Guidance literature:

With ethanol; sodium; at 10 ℃;

Reference yield: 100.0%

ethyl 4-(4-fluorophenyl)-2,4-dioxobutanoate (31686-94-9) → 3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid ethyl ester (866588-11-6)

Guidance literature:

With hydrazine; In ethanol; for 1h; Heating / reflux;

upstream raw materials:

1-(4-fluorophenyl)ethanone

oxalic acid diethyl ester

Downstream raw materials:

5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester

ethyl 5-(4-fluorophenyl)isoxazole-3-carboxylate

5-(4-fluorophenyl)isoxazole-3-carbaldehyde

[5-(4-fluoro-phenyl)-isoxazol-3-yl]-methanol