11-Hydroxy-sugiol

Base Information

Chemical Name:11-Hydroxy-sugiol
CAS No.:88664-08-8
Molecular Formula:C₂₀H₂₈O₃
Molecular Weight:316.441
Hs Code.:

Synonyms:11-Hydroxylsugiol;12-O-deMethylcryptojapanol;Demethylcryptojaponol;

Suppliers and Price of 11-Hydroxy-sugiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
11-Hydroxy-sugiol
5mg
$ 470.00

Arctom
11-hydroxy-sugiol
5mg
$ 932.73

ApexBio Technology
11-hydroxy-sugiol
5mg
$ 900.00

Total 19 raw suppliers

Chemical Property of 11-Hydroxy-sugiol

Chemical Property:

Melting Point:192-194℃
Boiling Point:482.2±45.0 °C(Predicted)
PKA:8.55±0.60(Predicted)
PSA：57.53000
Density:1.110±0.06 g/cm3 (20 oC 760 Torr)
LogP:4.89160

Purity/Quality:

95%-98% ^*data from raw suppliers

11-Hydroxy-sugiol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 11-Hydroxy-sugiol

There total 9 articles about 11-Hydroxy-sugiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.3%

: 62691-22-9
(+)-11-acetoxy-12-benzoyloxy-8,11,13-abietatrien-7-one

: 88664-08-8
(4aS,10aS)-2,3,4,4a,10,10a-hexahydro-5,6-dihydroxy-1,1,4a-trimethyl-7-(1-methylethyl)phenanthren-9(1H)-one

Guidance literature:: With sodium hydrogencarbonate; In methanol; water; for 1.5h; Heating;
DOI:10.1016/S0968-0896(00)00253-4

Reference yield:

: 70614-86-7
(4aS,10aS)-7-isopropyl-6-methoxy-1,1,4a-trimethyl-1,2,3,4,4a,10a-hexahydrophenanthrene

: 88664-08-8
(4aS,10aS)-2,3,4,4a,10,10a-hexahydro-5,6-dihydroxy-1,1,4a-trimethyl-7-(1-methylethyl)phenanthren-9(1H)-one

Guidance literature:: Multi-step reaction with 6 steps

1: 98.3 percent / H₂ / Pd/C / ethyl acetate / 24 h / 20 °C

2: 94.9 percent / BBr₃ / CH₂Cl₂ / 2 h / 0 - 5 °C

3: 71.4 percent / CHCl₃ / 7 h / 20 °C

4: 76.7 percent / TsOH / toluene / 5 h / Heating

5: 65.9 percent / CrO₃ / acetic acid / 8 h / 20 °C

6: 96.3 percent / NaHCO₃ / methanol; H₂O / 1.5 h / Heating

With chromium(VI) oxide; hydrogen; boron tribromide; sodium hydrogencarbonate; toluene-4-sulfonic acid; palladium on activated charcoal; In methanol; dichloromethane; chloroform; water; acetic acid; ethyl acetate; toluene; 1: hydrogenation / 2: hydrolysis / 3: oxidation; esterification / 4: acetylation / 5: oxidation / 6: hydrolysis;
DOI:10.1016/S0968-0896(00)00253-4

Reference yield:

: (4aS,9R,10aS)-6-Methoxy-1,1,4a-trimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-9-carboxylic acid

: 88664-08-8
(4aS,10aS)-2,3,4,4a,10,10a-hexahydro-5,6-dihydroxy-1,1,4a-trimethyl-7-(1-methylethyl)phenanthren-9(1H)-one

Guidance literature:: Multi-step reaction with 8 steps

1: 80.9 percent / AlCl₃ / CH₂Cl₂ / 40 h / 40 °C

2: 87.4 percent / Pb(OAc)4; Cu(OAc)2 / quinoline / 16 h / 125 °C

3: 98.3 percent / H₂ / Pd/C / ethyl acetate / 24 h / 20 °C

4: 94.9 percent / BBr₃ / CH₂Cl₂ / 2 h / 0 - 5 °C

5: 71.4 percent / CHCl₃ / 7 h / 20 °C

6: 76.7 percent / TsOH / toluene / 5 h / Heating

7: 65.9 percent / CrO₃ / acetic acid / 8 h / 20 °C

8: 96.3 percent / NaHCO₃ / methanol; H₂O / 1.5 h / Heating

With chromium(VI) oxide; lead(IV) acetate; aluminium trichloride; copper diacetate; hydrogen; boron tribromide; sodium hydrogencarbonate; toluene-4-sulfonic acid; palladium on activated charcoal; In quinoline; methanol; dichloromethane; chloroform; water; acetic acid; ethyl acetate; toluene; 1: Friedel-Crafts alkylation / 2: decarboxylation / 3: hydrogenation / 4: hydrolysis / 5: oxidation; esterification / 6: acetylation / 7: oxidation / 8: hydrolysis;
DOI:10.1016/S0968-0896(00)00253-4