4-(Dimethylamino)-2,5-dimethoxybenzaldehyde

Base Information

Chemical Name:4-(Dimethylamino)-2,5-dimethoxybenzaldehyde
CAS No.:88753-04-2
Molecular Formula:C₁₁H₁₅NO₃
Molecular Weight:209.245
Hs Code.:
NSC Number:156547
DSSTox Substance ID:DTXSID20303080
Wikidata:Q82048193
ChEMBL ID:CHEMBL1894579

Synonyms:4-(dimethylamino)-2,5-dimethoxybenzaldehyde;88753-04-2;NSC156547;CHEMBL1894579;SCHEMBL15985695;DTXSID20303080;NSC-156547;NCGC00188246-01;NCGC00188246-02;NCGC00188246-03;AT-051/43422773

Suppliers and Price of 4-(Dimethylamino)-2,5-dimethoxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-(Dimethylamino)-2,5-dimethoxybenzaldehyde

Chemical Property:

Vapor Pressure:0.000262mmHg at 25°C
Boiling Point:323.4°Cat760mmHg
Flash Point:149.4°C
Density:1.118g/cm³
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:209.10519334
Heavy Atom Count:15
Complexity:208

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C1=C(C=C(C(=C1)OC)C=O)OC

Technology Process of 4-(Dimethylamino)-2,5-dimethoxybenzaldehyde

There total 1 articles about 4-(Dimethylamino)-2,5-dimethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 4031-94-1
2,5-dimethoxy-N,N-dimethylaniline

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 88753-04-2
2,5-dimethoxy-4-dimethylaminobenzaldehyde

Guidance literature:: With trichlorophosphate; at 0 - 65 ℃; Inert atmosphere;
DOI:10.1021/ja510602z

Reference yield: 74.0%

: 1779-49-3
Methyltriphenylphosphonium bromide

: 88753-04-2
2,5-dimethoxy-4-dimethylaminobenzaldehyde

: 2,5-dimethoxy-4-dimethylaminostyrene

Guidance literature:: Methyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 0.5h; Inert atmosphere;

2,5-dimethoxy-4-dimethylaminobenzaldehyde; In tetrahydrofuran; hexane; Inert atmosphere;
DOI:10.1021/ja510602z

Reference yield:

: 88753-04-2
2,5-dimethoxy-4-dimethylaminobenzaldehyde

: 5-((E)-4-((E)-4-(dimethylamino)-2,5-dimethoxystyryl)styryl)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzenesulfonic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / 20 °C / Inert atmosphere

1.2: Inert atmosphere

2.1: palladium diacetate; tris-(o-tolyl)phosphine; triethylamine / N,N-dimethyl-formamide / 20 h / 110 °C / Inert atmosphere; Sealed tube

3.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 30 °C / Inert atmosphere

3.2: Inert atmosphere

4.1: palladium diacetate; tris-(o-tolyl)phosphine; triethylamine / N,N-dimethyl-formamide / 18 h / 110 °C / Inert atmosphere; Sealed tube

With n-butyllithium; palladium diacetate; triethylamine; tris-(o-tolyl)phosphine; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1021/ja510602z