Spiro[chroMan-2,4'-piperidine]

Base Information

Chemical Name:Spiro[chroMan-2,4'-piperidine]
CAS No.:147372-85-8
Molecular Formula:C13H17NO
Molecular Weight:203.284
Hs Code.:2934999090
Mol file:147372-85-8.mol

Synonyms:3,4-DIHYDROSPIRO[CHROMENE-2,4'-PIPERIDINE] HYDROCHLORIDE;spiro[chromane-2,4'-piperidine];spiro[chromane-2,4'-piperidine] hydrochloride;3,4-Dihydrospiro[chromene-2,4'-piperidine];Spiro[chroMan-2,4-piperidine];

Suppliers and Price of Spiro[chroMan-2,4'-piperidine]

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Spiro[chroman-2,4'-piperidine] 95+%
5g
$ 1305.00

Crysdot
Spiro[chroman-2,4'-piperidine] 95+%
1g
$ 434.00

Chemenu
Spiro[chroman-2,4''-piperidine] 95%
1g
$ 926.00

American Custom Chemicals Corporation
3,4-DIHYDRO-SPIRO-[2H-1-BENZOPYRAN-2,4'-PIPERIDINE] 95.00%
5MG
$ 503.60

Alichem
Spiro[chroman-2,4'-piperidine]
1g
$ 1089.00

Alichem
Spiro[chroman-2,4'-piperidine]
250mg
$ 419.76

Total 13 raw suppliers

Chemical Property of Spiro[chroMan-2,4'-piperidine]

Chemical Property:

Boiling Point:336.7±42.0 °C(Predicted)
PKA:10.34±0.20(Predicted)
PSA：21.26000
Density:1.12±0.1 g/cm3(Predicted)
LogP:2.46260
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Spiro[chroman-2,4'-piperidine] 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Spiro[chroMan-2,4'-piperidine]

There total 9 articles about Spiro[chroMan-2,4'-piperidine] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: benzyl spiro[chroman-2,4'-piperidine]-1'-carboxylate

: 147372-85-8
spiro[chroman-2,4’-piperidine]

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; for 16h;

Reference yield:

: 19099-93-5
benzyl 4-oxo-1-piperidinecarboxylate

: 147372-85-8
spiro[chroman-2,4’-piperidine]

Guidance literature:: Multi-step reaction with 3 steps

1: pyrrolidine / methanol / 20 h / 80 °C

2: acetic acid / zinc / 3 h / 100 °C

3: hydrogen / palladium 10% on activated carbon / methanol / 16 h

With pyrrolidine; hydrogen; acetic acid; palladium 10% on activated carbon; zinc; In methanol;

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 147372-85-8
spiro[chroman-2,4’-piperidine]

Guidance literature:: Multi-step reaction with 4 steps

1: pyrrolidine

2: aq. HCl / ethanol / Heating

3: NaBH₄

4: H₂ / Pd(OH)2/C / ethanol

With pyrrolidine; hydrogenchloride; sodium tetrahydroborate; hydrogen; palladium dihydroxide; In ethanol;
DOI:10.1016/S0960-894X(97)10199-8