2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine

Base Information

Chemical Name:2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine
CAS No.:889447-20-5
Molecular Formula:C6H3ClIN3
Molecular Weight:279.467
Hs Code.:
DSSTox Substance ID:DTXSID701272930
Mol file:889447-20-5.mol

Synonyms:2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine;889447-20-5;SCHEMBL650607;JYAUQLBWOPEZFN-UHFFFAOYSA-N;DTXSID701272930;MFCD12755891;AKOS024260309;PB25471;AS-33593;CS-0051924;FT-0705524;A861376

Suppliers and Price of 2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine
1 g
$ 675.00

Matrix Scientific
2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine
1g
$ 1286.00

Crysdot
2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine 95+%
1g
$ 611.00

Crysdot
2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine 95+%
250mg
$ 299.00

Chemenu
2-chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine 95%+
100mg
$ 290.00

Chemenu
2-chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine 95%+
250mg
$ 564.00

Chemenu
2-chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine 95%+
1g
$ 1008.00

Atlantic Research Chemicals
2-Chloro-7-iodo-5H-pyrolo[2,3-b]pyrazine 95%
1gm:
$ 660.96

American Custom Chemicals Corporation
2-CHLORO-7-IODO-5H-PYRROLO[2,3-B]PYRAZINE 95.00%
5MG
$ 454.04

Alichem
2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine
25g
$ 6633.00

Total 24 raw suppliers

Chemical Property of 2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine

Chemical Property:

PKA:9.13±0.50(Predicted)
PSA：41.57000
Density:2.284±0.06 g/cm3(Predicted)
LogP:2.21590
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:278.90602
Heavy Atom Count:11
Complexity:157

Purity/Quality:

99%, ^*data from raw suppliers

2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C2=NC(=CN=C2N1)Cl)I

Technology Process of 2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine

There total 4 articles about 2-Chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 889447-19-2
2-chloro-5H-pyrrolo[2,3-b]pyrazine

: 889447-20-5
2-chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine

Guidance literature:: With N-iodo-succinimide; In acetone; at 20 ℃; for 12h;

Reference yield:

: 1244776-64-4
5-chloro-3-((trimethylsilyl)ethynyl)pyrazine-2-amine

: 889447-20-5
2-chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 120 °C / Sealed tube

2: N-iodo-succinimide / 2-methyltetrahydrofuran / 20 °C

With N-iodo-succinimide; potassium tert-butylate; In tetrahydrofuran; 2-methyltetrahydrofuran;

Reference yield:

: 875781-43-4
2-bromo-5H-pyrrolo[2,3-b]pyrazine

: 889447-20-5
2-chloro-7-iodo-5H-pyrrolo[2,3-b]pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate; triethylamine / 1,4-dioxane / 6 h / 110 °C

2: N-iodo-succinimide / acetone / 12 h / 20 °C

With N-iodo-succinimide; triethylamine; trichlorophosphate; In 1,4-dioxane; acetone;