IGF-1 LR3

Base Information

• Chemical Name: IGF-1 LR3
• CAS No.: 946870-92-4
• Molecular Weight: 0.00000

Synonyms:2: PN: CN101007848 SEQID: 2 claimed DNA;DNA (Human Insulin-like growth factor I (LR3 IGF-1, long chain R3) gene);

Chemical Property of IGF-1 LR3

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

99% ,99.9%, ^*data from raw suppliers

Safty Information:

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Useful:

• Description: Long arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in that it possesses an arginine instead of a glutamic acid at the third position in its amino acid sequence ("arginine 3"), and also has an additional 13 amino acids at its N-terminus (MFPAMPLLSLFVN) ("long"), for a total of 83 amino acids (relative to the 70 of IGF-1).
• Uses: The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability.As a result, it is approximately three times more potent than IGF-1,and possesses a significantly longer half-life of about 20–30 hours (relative to IGF-1's half-life of about 12–15 hours).

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