2-butyl-1,6-dihydro-4-methyl-6-oxo-5-Pyrimidineacetic acid

Base Information

Chemical Name:2-butyl-1,6-dihydro-4-methyl-6-oxo-5-Pyrimidineacetic acid
CAS No.:1315478-16-0
Molecular Formula:C11H16N2O3
Molecular Weight:224.26
Hs Code.:
Mol file:1315478-16-0.mol

Synonyms:2-butyl-1,6-dihydro-4-Methyl-6-oxo-5-PyriMidineacetic acid;5-Pyrimidineacetic acid, 2-butyl-1,6-dihydro-4-methyl-6-oxo-;(2-Butyl-4-methyl-6-oxo-1,6-dihydro-5-pyrimidinyl)acetic acid;2-(2-Butyl-1,6-dihydro-4-methyl-6-oxopyrimmidin-5-yl) acetic acid (BEM-II)

Suppliers and Price of 2-butyl-1,6-dihydro-4-methyl-6-oxo-5-Pyrimidineacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 18 raw suppliers

Chemical Property of 2-butyl-1,6-dihydro-4-methyl-6-oxo-5-Pyrimidineacetic acid

Chemical Property:

Appearance/Colour:white powders
Boiling Point:386.9±44.0 °C(Predicted)
PKA:4.00±0.10(Predicted)
PSA：83.31000
Density:1.24±0.1 g/cm3 (20 oC 760 Torr)
LogP:1.46030

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-butyl-1,6-dihydro-4-methyl-6-oxo-5-Pyrimidineacetic acid

There total 3 articles about 2-butyl-1,6-dihydro-4-methyl-6-oxo-5-Pyrimidineacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1115-30-6
diethyl acetylsuccinate

: 18257-46-0
pentanamidine hydrochloride

: 1315478-16-0
2-(2-n-butyl-4-hydroxy-6-methyl-pyrimidin-5-yl)acetic acid

Guidance literature:: With potassium hydroxide; In methanol; at 20 ℃; for 15h;

Reference yield: 70.0%

: 10420-33-4
dimethyl 2-acetylsuccinate

: 18257-46-0
pentanamidine hydrochloride

: 1315478-16-0
2-(2-n-butyl-4-hydroxy-6-methyl-pyrimidin-5-yl)acetic acid

Guidance literature:: dimethyl 2-acetylsuccinate; pentanamidine hydrochloride; With methanol; potassium hydroxide; at 20 ℃; for 15h;

With hydrogenchloride; In water; pH=4;

Reference yield:

: 110-59-8
pentanonitrile

: 1315478-16-0
2-(2-n-butyl-4-hydroxy-6-methyl-pyrimidin-5-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogenchloride / methanol / 9 h / 0 - 10 °C

1.2: 0 - 20 °C / pH 8.5

2.1: potassium hydroxide / methanol / 15 h / 20 °C

With hydrogenchloride; potassium hydroxide; In methanol;