QUINOLINE, 1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO-

Base Information

Chemical Name:QUINOLINE, 1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO-
CAS No.:94193-47-2
Molecular Formula:C20H20N2O5
Molecular Weight:0
Hs Code.:2933499090
Mol file:94193-47-2.mol

Synonyms:QUINOLINE, 1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO-

Suppliers and Price of QUINOLINE, 1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO-QUINOLINE 95.00%
5MG
$ 502.12

Total 3 raw suppliers

Chemical Property of QUINOLINE, 1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO-

Chemical Property:

Vapor Pressure:4.8E-17mmHg at 25°C
Boiling Point:655.2°C at 760 mmHg
Flash Point:350.1°C
PSA：92.43000
Density:1.299g/cm³
LogP:4.13390

Purity/Quality:: 1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO-QUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of QUINOLINE, 1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO-

There total 2 articles about QUINOLINE, 1-[4-(3-FORMYL-4-NITROPHENOXY)-1-OXOBUTYL]-1,2,3,4-TETRAHYDRO- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 94193-36-9
4-(3-formyl-4-nitrophenyl)oxybutanoic acid

: 94193-47-2
5-[4-(3,4-Dihydro-2H-quinolin-1-yl)-4-oxo-butoxy]-2-nitro-benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride / benzene; dimethylformamide / 0.5 h

2: triethylamine, 4-(dimethylamino)pyridine / tetrahydrofuran / 2 h / Ambient temperature

With dmap; oxalyl dichloride; triethylamine; In tetrahydrofuran; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00385a012

Reference yield:

: 635-46-1
1,2,3,4-tetrahydroisoquinoline

: 94193-37-0
4-(3-Formyl-4-nitro-phenoxy)-butyryl chloride

: 94193-47-2
5-[4-(3,4-Dihydro-2H-quinolin-1-yl)-4-oxo-butoxy]-2-nitro-benzaldehyde

Guidance literature:: With dmap; triethylamine; In tetrahydrofuran; for 2h; Yield given; Ambient temperature;
DOI:10.1021/jm00385a012

Reference yield:

: 94193-47-2
5-[4-(3,4-Dihydro-2H-quinolin-1-yl)-4-oxo-butoxy]-2-nitro-benzaldehyde

: {2-Amino-5-[4-(3,4-dihydro-2H-quinolin-1-yl)-4-oxo-butoxy]-benzylamino}-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) AcONa / ethanol / 0.5 h

2: NaBH₃CN / ethanol / 3 h

3: H₂ / 10percent Pd/C / ethanol

With hydrogen; sodium acetate; sodium cyanoborohydride; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00385a012