(1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol

Base Information

Chemical Name:(1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol
CAS No.:1094223-48-9
Molecular Formula:C10H14ClN3O
Molecular Weight:227.69066
Hs Code.:2933990090
DSSTox Substance ID:DTXSID00599767
Wikidata:Q82495708
Mol file:1094223-48-9.mol

Synonyms:1094223-48-9;(1-(6-chloropyridazin-3-yl)piperidin-4-yl)methanol;[1-(6-CHLOROPYRIDAZIN-3-YL)PIPERIDIN-4-YL]METHANOL;[1-(6-Chloro-3-pyridazinyl)-4-piperidyl]methanol;4-Piperidinemethanol,1-(6-chloro-3-pyridazinyl)-;SCHEMBL9198277;DTXSID00599767;MFCD11205547;AKOS009320247;AS-31976;SY005709;DB-027224;CS-0450932;A895044;F1967-2176

Suppliers and Price of (1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol 97%
10g
$ 385.00

Chemenu
(1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol 97%
10g
$ 364.00

American Custom Chemicals Corporation
[1-(6-CHLOROPYRIDAZIN-3-YL)PIPERIDIN-4-YL]METHANOL 95.00%
5G
$ 1420.65

AK Scientific
[1-(6-Chloropyridazin-3-yl)piperidin-4-yl]methanol
250mg
$ 108.00

Total 6 raw suppliers

Chemical Property of (1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol

Chemical Property:

Boiling Point:455.7±30.0 °C(Predicted)
PKA:14.94±0.10(Predicted)
PSA：49.25000
Density:1.274±0.06 g/cm3(Predicted)
LogP:1.40370
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:227.0825398
Heavy Atom Count:15
Complexity:197

Purity/Quality:

97% ^*data from raw suppliers

(1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1CO)C2=NN=C(C=C2)Cl

Technology Process of (1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol

There total 1 articles about (1-(6-Chloropyridazin-3-yl)piperidin-4-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 6457-49-4
4-piperidinemethanol

: 141-30-0
3,6-dichlorpyridazine

: 1094223-48-9
(1-(6-chloropyridazin-3-yl)piperidin-4-yl)methanol

Guidance literature:: With N-ethyl-N,N-diisopropylamine; at 90 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jm500118j

Reference yield:

: 1094223-48-9
(1-(6-chloropyridazin-3-yl)piperidin-4-yl)methanol

: 1588959-00-5
9-((1r,4r)-4-methylcyclohexyl)-N-(6-(4-((methylsulfonyl)methyl)-piperidin-1-yl)pyridazin-3-yl)-9H-pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidin-2-amine

Guidance literature:: Multi-step reaction with 4 steps

1: triethylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere

2: N,N-dimethyl-formamide / 20 °C / Inert atmosphere

3: Oxone / water; methanol / 20 °C / Inert atmosphere

4: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate / 1,4-dioxane / 120 °C / Inert atmosphere

With Oxone; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium t-butanolate; In 1,4-dioxane; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jm500118j