2-propylquinoline-4-carbohydrazide

Base Information

• Chemical Name: 2-propylquinoline-4-carbohydrazide
• CAS No.: 7466-63-9
• Molecular Formula: C₁₃H₁₅N₃O
• Molecular Weight: 229.282
• Mol file: 7466-63-9.mol

Synonyms:NSC402727

Chemical Property of 2-propylquinoline-4-carbohydrazide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.184g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-propylquinoline-4-carbohydrazide

There total 4 articles about 2-propylquinoline-4-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-propylquinoline-4-carboxylic acid (1019-03-0) → 2-propylquinoline-4-carbohydrazide (7466-63-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / 1 h / Reflux

2: hydrazine hydrate / ethanol / 1 h / Reflux

With sulfuric acid; hydrazine hydrate; In ethanol;

DOI:10.1002/jhet.3050

Reference yield:

indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) → 2-propylquinoline-4-carbohydrazide (7466-63-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium hydroxide / water / 0.5 h / 20 °C

1.2: 9 h / 80 °C

2.1: sulfuric acid / 1 h / Reflux

3.1: hydrazine hydrate / ethanol / 1 h / Reflux

With sulfuric acid; hydrazine hydrate; potassium hydroxide; In ethanol; water; 1.1: |Pfitzinger Quinoline Synthesis / 1.2: |Pfitzinger Quinoline Synthesis;

DOI:10.1002/jhet.3050

Reference yield:

2-Pentanone (107-87-9) → 2-propylquinoline-4-carbohydrazide (7466-63-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: potassium hydroxide / water / 0.5 h / 20 °C

1.2: 9 h / 80 °C

2.1: sulfuric acid / 1 h / Reflux

3.1: hydrazine hydrate / ethanol / 1 h / Reflux

With sulfuric acid; hydrazine hydrate; potassium hydroxide; In ethanol; water; 1.1: |Pfitzinger Quinoline Synthesis / 1.2: |Pfitzinger Quinoline Synthesis;

DOI:10.1002/jhet.3050

upstream raw materials:

2-propylquinoline-4-carboxylic acid

indole-2,3-dione

2-Pentanone

Refernces