(1-Isopropylcyclopropyl)amine hydrochloride

Base Information

• Chemical Name: (1-Isopropylcyclopropyl)amine hydrochloride
• CAS No.: 1174526-66-9
• Molecular Formula: C6H13N
• Molecular Weight: 99.17
• Hs Code.: 2921300090
• Mol file: 1174526-66-9.mol

Synonyms:(1-Isopropylcyclopropyl)amine hydrochloride;1-isopropylcyclopropanamine

Chemical Property of (1-Isopropylcyclopropyl)amine hydrochloride

Chemical Property:

• PSA: 26.02000
• LogP: 1.83400

Purity/Quality:

98%min ^*data from raw suppliers

(1-Isopropylcyclopropyl)amine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1-Isopropylcyclopropyl)amine hydrochloride

There total 2 articles about (1-Isopropylcyclopropyl)amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.8%

Isobutyronitrile (78-82-0) + ethylmagnesium bromide (925-90-6) → 1-isopropylcyclopropan-1-amine (1174526-66-9)

Guidance literature:

Isobutyronitrile; ethylmagnesium bromide; With titanium(IV) isopropylate; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 2h;

With boron trifluoride diethyl etherate; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 14h;

Reference yield:

→ 1-isopropylcyclopropan-1-amine (1174526-66-9)

Guidance literature:

Reference yield:

1-isopropylcyclopropan-1-amine (1174526-66-9) + 2-bromobenzoic acid chloride (7154-66-7) → C13H16BrNO

Guidance literature:

1-isopropylcyclopropan-1-amine; With sodium carbonate; In water; at 20 ℃; for 0.333333h;

2-bromobenzoic acid chloride; In water; at 20 ℃; for 15h;

DOI:10.1021/acs.orglett.9b00627

upstream raw materials:

Isobutyronitrile

ethylmagnesium bromide

Refernces

• 1、 -. "HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE". Page 77-78. . Retrieved 2010/02/07.