AP20187

Base Information

• Chemical Name: AP20187
• CAS No.: 195514-80-8
• Molecular Formula: C82H107N5O20
• Molecular Weight: 1482.77
• Mol file: 195514-80-8.mol

Synonyms:AP20187

Chemical Property of AP20187

Chemical Property:

• PSA: 265.42000
• LogP: 11.88220
• Solubility.: ≥74.14 mg/mL in DMSO; ≥100 mg/mL in EtOH

Purity/Quality:

98%Min ^*data from raw suppliers

AP20187 ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of AP20187

There total 1 articles about AP20187 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

(S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylic acid (195202-09-6) + C44H57N3O10 (1392284-65-9) → AP20187 (195514-80-8)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20 ℃; for 50h;

Reference yield: 85.0%

methanesulfonic acid (75-75-2,98527-29-8) + AP20187 (195514-80-8) → AP20187 mesylate salt (1392284-66-0)

Guidance literature:

In ethyl acetate; at 0 ℃; for 0.333333h;

upstream raw materials:

(S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylic acid

C₄₄H₅₇N₃O₁₀

Downstream raw materials:

AP₂₀₁₈₇ mesylate salt