3,5-DI(Thiophen-2-YL)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Base Information

Chemical Name:3,5-DI(Thiophen-2-YL)-4,5-dihydro-1H-pyrazole-1-carbothioamide
CAS No.:870680-39-0
Molecular Formula:C₁₂H₁₁N₃S₃
Molecular Weight:293.437
Hs Code.:
ChEMBL ID:CHEMBL224191
DSSTox Substance ID:DTXSID00467654
Mol file:870680-39-0.mol

Synonyms:870680-39-0;3,5-DI(THIOPHEN-2-YL)-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOTHIOAMIDE;CHEMBL224191;BDBM11013;DTXSID00467654;1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazole deriv. 10;3,5-bis(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Suppliers and Price of 3,5-DI(Thiophen-2-YL)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,5-DI(THIOPHEN-2-YL)-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOTHIOAMIDE 98.00%
5MG
$ 502.68

Total 3 raw suppliers

Chemical Property of 3,5-DI(Thiophen-2-YL)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Chemical Property:

PSA：130.19000
LogP:3.27810
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:293.01151088
Heavy Atom Count:18
Complexity:372

Purity/Quality:

97% ^*data from raw suppliers

3,5-DI(THIOPHEN-2-YL)-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOTHIOAMIDE 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(N(N=C1C2=CC=CS2)C(=S)N)C3=CC=CS3

Technology Process of 3,5-DI(Thiophen-2-YL)-4,5-dihydro-1H-pyrazole-1-carbothioamide

There total 5 articles about 3,5-DI(Thiophen-2-YL)-4,5-dihydro-1H-pyrazole-1-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 2309-48-0
1,3-di(thiophen-2-yl)propenone

: 79-19-6
thiosemicarbazide

: 870680-39-0
3,5-di(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Guidance literature:: With sodium hydroxide; In ethanol; for 6h; Reflux;
DOI:10.21608/ejchem.2021.95621.4488

Reference yield:

: 98-03-3
thiophene-2-carbaldehyde

: 870680-39-0
3,5-di(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Guidance literature:: Multi-step reaction with 2 steps

1: aq. KOH / ethanol

2: 58 percent / KOH / ethanol / Heating

With potassium hydroxide; In ethanol;
DOI:10.1021/jm040903t

Reference yield:

: 88-15-3,97511-16-5
2-Acetylthiophene

: 870680-39-0
3,5-di(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-carbothioamide

Guidance literature:: Multi-step reaction with 2 steps

1: aq. KOH / ethanol

2: 58 percent / KOH / ethanol / Heating

With potassium hydroxide; In ethanol;
DOI:10.1021/jm040903t