(Diphenylphosphino)methanethiol

Base Information

Chemical Name:(Diphenylphosphino)methanethiol
CAS No.:324753-16-4
Molecular Formula:C13H13PS
Molecular Weight:232.286
Hs Code.:2930909090
DSSTox Substance ID:DTXSID50459468
Nikkaji Number:J1.960.226E
Mol file:324753-16-4.mol

Synonyms:(DIPHENYLPHOSPHINO)METHANETHIOL;324753-16-4;Diphenylphosphanylmethanethiol;(DIPHENYLPHOSPHANYL)METHANETHIOL;1-(DIPHENYLPHOSPHINO)METHANETHIOL;diphenylphosphinomethanethiol;SCHEMBL81044;DTXSID50459468;IGEZSSBBLDNMPJ-UHFFFAOYSA-N;FT-0667671;(Diphenylphosphino)methanethiol Preparation Kit;J-018750

Suppliers and Price of (Diphenylphosphino)methanethiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(Diphenylphosphino)methanethiolPreparationKit
25mg
$ 125.00

American Custom Chemicals Corporation
(DIPHENYLPHOSPHINO)METHANETHIOL 95.00%
250MG
$ 1871.10

American Custom Chemicals Corporation
(DIPHENYLPHOSPHINO)METHANETHIOL 95.00%
25MG
$ 739.20

Total 2 raw suppliers

Chemical Property of (Diphenylphosphino)methanethiol

Chemical Property:

Vapor Pressure:0.00041mmHg at 25°C
Boiling Point:326.4°C at 760 mmHg
PKA:9.09±0.10(Predicted)
Flash Point:151.2°C
PSA：52.39000
LogP:3.00660
Storage Temp.:Hygroscopic, -20?C Freezer, Under Inert Atmosphere
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly)
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:232.04755859
Heavy Atom Count:15
Complexity:153

Purity/Quality:

98% ^*data from raw suppliers

(Diphenylphosphino)methanethiolPreparationKit ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)P(CS)C2=CC=CC=C2
Uses Used for production of peptide thioester. (Diphenylphosphino)methanethiol used for production of peptide thioester

Technology Process of (Diphenylphosphino)methanethiol

There total 8 articles about (Diphenylphosphino)methanethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 324753-11-9
thioacetic acid S-[(diphenylphosphanyl)methyl] ester

: 324753-16-4
(diphenylphosphanyl)methanethiol

Guidance literature:: With sodium hydroxide; In methanol;
DOI:10.1021/jo025631l

Reference yield:

: 1806-49-1
diphenyl(chloromethyl)phosphine oxide

: 324753-16-4
(diphenylphosphanyl)methanethiol

Guidance literature:: Multi-step reaction with 3 steps

1: dimethylformamide

2: trichlorosilane / CHCl₃ / 72 h

3: NaOH / methanol / 1.5 h

With sodium hydroxide; trichlorosilane; In methanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1021/jo0620056

Reference yield:

: 324753-14-2
S-(diphenylphosphinoyl)methyl ethanethioate

: 324753-16-4
(diphenylphosphanyl)methanethiol

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorosilane / CHCl₃ / 72 h

2: NaOH / methanol / 1.5 h

With sodium hydroxide; trichlorosilane; In methanol; chloroform;
DOI:10.1021/jo0620056